Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27982324 | 0.84 | HTR6 (0.33) | HTR6 | |
| SCHEMBL28959025 | 0.81 | HTR6 (0.30) | HTR6 | |
| SCHEMBL27707863 | 0.76 | — | — | |
| SCHEMBL27571864 | 0.74 | OPRM1 (0.37) | — | |
| SCHEMBL28959006 | 0.71 | — | — | |
| SCHEMBL27473920 | 0.71 | ESR1 (0.51) | MAOAMAOBPRKCIHTR6ESR2 | |
| SCHEMBL27594349 | 0.70 | XDH (0.34) | ALDH1A1HSP90AA1 | |
| SCHEMBL22048215 | 0.69 | — | — | |
| SCHEMBL28958979 | 0.68 | MEN1 (0.30) | ALDH1A1LMNA | |
| SCHEMBL27523226 | 0.68 | ESR1 (0.43) | MAOAMAOBPRKCIESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621070-B | Synthesis method of 3, 4-dihydronaphthalene-1 (2H) -one derivative | 上海陶术生物科技有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-114621070-A | Synthesis method of 3, 4-dihydronaphthalene-1 (2H) -ketone derivative | 上海陶术生物科技有限公司 | 2022-06-14 | — | — | CN | claimed |
| CN-114621070-B | Synthesis method of 3, 4-dihydronaphthalene-1 (2H) -one derivative | 上海陶术生物科技有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-114621070-B | Synthesis method of 3, 4-dihydronaphthalene-1 (2H) -one derivative | 上海陶术生物科技有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-114621070-A | Synthesis method of 3, 4-dihydronaphthalene-1 (2H) -ketone derivative | 上海陶术生物科技有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-114621070-A | Synthesis method of 3, 4-dihydronaphthalene-1 (2H) -ketone derivative | 上海陶术生物科技有限公司 | 2022-06-14 | — | — | CN | disclosed |