Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 16/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3113605 | 0.83 | MAPK1 (0.49) | TSHRMAPK1KDM4EMAPT | |
| SCHEMBL6466375 | 0.82 | DRD1 (0.37) | MAPT | |
| SCHEMBL29190283 | 0.77 | APP (0.41) | APPMAPK1MAPT | |
| Hydrochloric Acid SCHEMBL29190230 | 0.76 | APP (0.40) | APPMAPK1MAPT | |
| SCHEMBL2095043 | 0.76 | GLA (0.55) | APPTSHRMAPK1KDM4EMAPT | |
| SCHEMBL6524362 | 0.72 | KIF11 (0.41) | APPKIF11 | |
| SCHEMBL28806812 | 0.72 | KIF11 (0.41) | APPKIF11 | |
| SCHEMBL29162098 | 0.72 | KDM4E (0.40) | APPKDM4EMAPT | |
| SCHEMBL28896114 | 0.72 | P2RX3 (0.36) | MAPT | |
| SCHEMBL3976268 | 0.71 | APP (0.57) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677723-B | 5-HT2A receptor antagonists and their use for treating central nervous system disorders | 瀚远医药有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-115850204-B | Tetrahydrobenzothiophene derivative, and preparation method and application thereof | 烟台大学 | 2024-01-19 | — | — | CN | disclosed |
| CN-115850204-A | Tetrahydrobenzothiophene derivative and preparation method and application thereof | 烟台大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-113214289-B | 5-HT2A receptor antagonists and their use for the treatment of central nervous system disorders | 瀚远医药有限公司 | 2022-10-28 | — | — | CN | disclosed |