Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3732313 | 0.87 | MEN1 (0.46) | ALDH1A1ALOX15KMT2AMEN1LMNA | |
| SCHEMBL10602962 | 0.87 | PPARG (0.39) | KMT2AMEN1LMNASLC6A4 | |
| SCHEMBL28384768 | 0.87 | LDHA (0.47) | DRD1ALDH1A1ALOX15KMT2AMEN1 | |
| SCHEMBL2970016 | 0.86 | LTA4H (0.41) | ALDH1A1ALOX15KMT2AMEN1LMNA | |
| SCHEMBL29153373 | 0.82 | LMNA (0.33) | ALDH1A1KMT2AMEN1LMNASLC6A4 | |
| SCHEMBL17134135 | 0.82 | — | — | |
| SCHEMBL28895840 | 0.82 | GAA (0.44) | ALDH1A1KMT2AMEN1LMNAPKM | |
| SCHEMBL1414596 | 0.82 | DRD1 (0.63) | DRD1ALDH1A1KMT2ALMNAHPGD | |
| SCHEMBL8129120 | 0.82 | CA2 (0.48) | — | |
| SCHEMBL6640503 | 0.82 | TRPA1 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1125344-A | — | — | None | — | — | JP | disclosed |
| US-6849762-B2 | Process for preparing a trifluoroethoxy-substituted benzoic acid | MERCK PATENT GMBH (DE) | 2005-02-01 | — | — | US | disclosed |
| US-20030176721-A1 | Method for the production of trifluoroethoxy-substituted benzoic acids | MERCK PATENT GMBH (DE) | 2003-09-18 | — | — | US | disclosed |
| JP-H01125344-A | PRODUCTION OF 2,5-BIS(2,2,2-TRIFLUOROETHOXY)BENZOIC ACID | RIKER LAB INC | 1989-05-17 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176721-A1 | Method for the production of trifluoroethoxy-substituted benzoic acids | NISCH, TBCA, TALDO1 | DRD1 3037/4885ALDH1A1 298/4885ATM 4392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.