Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 3/20 | 0.31 |
| ▸ | TPO | P07202 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Verdiperstat SCHEMBL23225670 | 0.78 | MPO (0.58) | MPOOPRM1TPO | |
| SCHEMBL21530655 | 0.58 | ADORA2A (0.53) | — | |
| SCHEMBL6073625 | 0.56 | MEN1 (0.37) | PDE5A | |
| SCHEMBL29530734 | 0.55 | SMN1; SMN2 (0.50) | ADRA1DADRA1AADRA1B | |
| SCHEMBL601831 | 0.54 | MEN1 (0.33) | — | |
| SCHEMBL7854878 | 0.54 | KDM4E (0.66) | — | |
| SCHEMBL39141 | 0.52 | — | — | |
| SCHEMBL8457566 | 0.52 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL23639740 | 0.52 | CYP1A2 (0.41) | — | |
| SCHEMBL7021446 | 0.52 | JAK2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403584-B | 2-thio-2, 3-dihydropyrimidine-4-one derivatives, pharmaceutical compositions, preparation methods and applications thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115403584-A | 2-thio-2, 3-dihydropyrimidine-4-one derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-29 | — | — | CN | disclosed |