Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18204101 | 0.88 | CHRM2 (0.30) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL15864296 | 0.83 | — | — | |
| SCHEMBL28720019 | 0.79 | LMNA (0.31) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28720018 | 0.79 | LMNA (0.31) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL18341170 | 0.79 | — | — | |
| SCHEMBL18625594 | 0.79 | — | — | |
| SCHEMBL29012324 | 0.78 | CHRM2 (0.30) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL29012326 | 0.78 | CHRM2 (0.30) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28487635 | 0.78 | PRKCA (0.41) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28487634 | 0.78 | PRKCA (0.41) | LMNACHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115413275-A | Substituted 1,1 , -biphenyl compounds and methods of use thereof | 爱彼特生物制药公司 | 2022-11-29 | — | — | CN | disclosed |