SCHEMBL28960552

SCHEMBL28960552

CONC(=O)c1ccc(CCl)cc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
RAB9A P51151 5/20 0.49
NPC1 O15118 4/20 0.49
MAPT P10636 4/20 0.47
LOXL2 Q9Y4K0 1/20 0.46
ALDH1A1 P00352 5/20 0.45
TDP1 Q9NUW8 1/20 0.45
HTT P42858 1/20 0.44
PLK1 P53350 1/20 0.43
HDAC3 O15379 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
NCOR2 Q9Y618 1/20 0.43
KDM1A O60341 1/20 0.43
KDM4E B2RXH2 2/20 0.42
LMNA P02545 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13296392 0.83 ALDH1A1 (0.64) CA1CA2RAB9ANPC1MAPT
SCHEMBL13878259 0.83 LOXL2 (0.67) CA1CA2RAB9ANPC1MAPT
SCHEMBL6846675 0.80 ALDH1A1 (0.63) CA1CA2MAPTALDH1A1HTT
SCHEMBL28590500 0.80 PLK1 (0.66) RAB9ANPC1ALDH1A1TDP1PLK1
SCHEMBL13009924 0.79 ALDH1A1 (0.54) CA1CA2RAB9ANPC1MAPT
SCHEMBL23512343 0.79 ALDH1A1 (0.58) CA1CA2RAB9ANPC1MAPT
SCHEMBL8638149 0.79 ALDH1A1 (0.61) RAB9ANPC1MAPTALDH1A1TDP1
SCHEMBL710211 0.79 PLK1 (0.68) CA1CA2HTTPLK1HDAC6
SCHEMBL200 0.79 LOXL2 (0.66) CA1CA2NPC1MAPTLOXL2
SCHEMBL20300383 0.78 ALDH1A1 (0.63) CA1CA2MAPTALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116574056-A Preparation method of fluoroisoquinolone compound 五邑大学 2023-08-11 CN disclosed
CN-115433222-A Preparation method and application of 2- (gem-difluoropropylene) benzamide compound 五邑大学 2022-12-06 CN disclosed