Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26687397 | 0.84 | MMP1 (0.60) | ALDH1A1LMNAKDM4EMAPTL3MBTL1 | |
| SCHEMBL27951738 | 0.81 | MAPT (0.70) | ALDH1A1KDM4EMAPTL3MBTL1RAB9A | |
| SCHEMBL14602517 | 0.81 | LMNA (0.55) | ALDH1A1LMNAKDM4EMAPTRAB9A | |
| SCHEMBL9402939 | 0.81 | CA1 (0.59) | ALDH1A1LMNAMAPTL3MBTL1RAB9A | |
| SCHEMBL28647585 | 0.81 | MAPT (0.50) | ALDH1A1LMNAMAPTL3MBTL1RAB9A | |
| SCHEMBL3645797 | 0.81 | ALDH1A1 (0.61) | ALDH1A1LMNAMAPTRAB9ANPC1 | |
| SCHEMBL13568181 | 0.81 | CSNK2A2 (0.49) | ALDH1A1LMNAKDM4EMAPTL3MBTL1 | |
| SCHEMBL28960899 | 0.80 | HDAC1 (0.55) | ALDH1A1LMNAKDM4EMAPTL3MBTL1 | |
| SCHEMBL13479797 | 0.80 | ALDH1A1 (0.57) | ALDH1A1LMNAKDM4EMAPTL3MBTL1 | |
| SCHEMBL8547880 | 0.79 | RAB9A (0.56) | LMNAKDM4EMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113735756-B | Method for synthesizing chiral 3, 3-disubstituted isoindolinone compound by rhodium catalysis | 陕西师范大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-116574056-A | Preparation method of fluoroisoquinolone compound | 五邑大学 | 2023-08-11 | — | — | CN | disclosed |
| CN-113149868-B | Method for synthesizing axichiral diene compound by trivalent rhodium catalysis | 陕西师范大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-115433222-A | Preparation method and application of 2- (gem-difluoropropylene) benzamide compound | 五邑大学 | 2022-12-06 | — | — | CN | disclosed |
| CN-113735756-A | Method for synthesizing chiral 3, 3-disubstituted isoindolinone compound by rhodium catalysis | 陕西师范大学 | 2021-12-03 | — | — | CN | disclosed |
| CN-113149868-A | Method for synthesizing axial chiral allene compound by using trivalent rhodium as catalyst | 陕西师范大学 | 2021-07-23 | — | — | CN | disclosed |
| CN-110305062-B | Substituted isoquinolone compound and synthesis method and application thereof | 广州医科大学 | 2021-01-05 | — | — | CN | disclosed |
| CN-107082761-B | Phenanthridinone or benzophenanthridinone derivative and synthesis method thereof | 上海大学 | 2020-04-03 | — | — | CN | disclosed |
| CN-102532021-B | Preparation method of 2-alkoxy-3,4-disubstituted isoquinoline-1(2H)-one derivatives | UNIV TIANJIN | 2013-10-16 | — | — | CN | disclosed |
| CN-103288711-A | Preparation method of 3-hydroxy-2-alkoxy-3-phenyl-isoindol-1(2H)-ketone derivatives | UNIV TIANJIN | 2013-09-11 | — | — | CN | disclosed |
| EP-1666551-B1 | Ink for ink jet-recording curable through irradiation and method for preparing lithographic printing plates using the same | FUJIFILM CORP (JP) | 2010-02-17 | — | — | EP | disclosed |
| US-7648997-B2 | Immunomodulators for inducing cytokine biosynthesis, for treatment of diseases including viral and neoplastic diseases; 1-[3-(Aminooxy)propyl]-2-propyl-1H-imidazo[4,5-c]quinolin-4-amine; N-[3-(4-Amino-2-propyl-1H-imidazo[4,5-c]quinolin-1-yl)propoxy]cyclopropanecarboxamide | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| US-7648997-B2 | Immunomodulators for inducing cytokine biosynthesis, for treatment of diseases including viral and neoplastic diseases; 1-[3-(Aminooxy)propyl]-2-propyl-1H-imidazo[4,5-c]quinolin-4-amine; N-[3-(4-Amino-2-propyl-1H-imidazo[4,5-c]quinolin-1-yl)propoxy]cyclopropanecarboxamide | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| US-7635181-B2 | Ink for ink jet-recording curable through irradiation with a radioactive ray and method for preparing lithographic printing plates using the same | FUJIFILM CORPORATION (JP) | 2009-12-22 | — | — | US | disclosed |
| US-7635181-B2 | Ink for ink jet-recording curable through irradiation with a radioactive ray and method for preparing lithographic printing plates using the same | FUJIFILM CORPORATION (JP) | 2009-12-22 | — | — | US | disclosed |
| US-20080114019-A1 | Hydroxylamine Substituted Imidazoquinolines | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2008-05-15 | — | — | US | disclosed |
| US-20080114019-A1 | Hydroxylamine Substituted Imidazoquinolines | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2008-05-15 | — | — | US | disclosed |
| US-5733935-A | EXCELLENT EFFECT FOR CONTROLLING WOOD-ROT FUNGI, PLANT DISEASES, FUNGI OF HUMANS AND ANIMALS, ALSO USEFUL AS INDUSTRIAL, AGRICULTURAL AND MEDICAL FUNGICIDE; IODOPROPARGYL DERIVATIVES | NIHON NOHYAKU CO., LTD. (JP) | 1998-03-31 | — | — | US | disclosed |
| EP-0751120-A2 | Hydroxylamine derivatives and fungicides containing the same | Nihon Nohyaku Co., Ltd. (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5319123-A | Reacting an N-alkoxyamide with an acyl halide in the presence of a hindered base | SANDOZ LTD. (CH) | 1994-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080114019-A1 | Hydroxylamine Substituted Imidazoquinolines | IFNG, IRF3, IL2 | ALDH1A1 513/4885LMNA 4187/4885KDM4E 1198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.