SCHEMBL28960941

SCHEMBL28960941

OCc1ccn(C(F)C(F)F)n1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.32
CCR1 P32246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21995159 0.83 CCR1 (0.33) P2RX7CCR1
SCHEMBL29052378 0.74 FYN (0.35)
SCHEMBL1064984 0.74 DYRK1A (0.39) P2RX7CCR1
SCHEMBL28994280 0.72
SCHEMBL29052395 0.72
SCHEMBL29232751 0.72
Ammonia Solution, Strong SCHEMBL29168206 0.71 LMNA (0.35)
SCHEMBL29005141 0.71 SMN1; SMN2 (0.36)
SCHEMBL29220564 0.71
SCHEMBL29052704 0.69 ALDH1A1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117881661-A Condensed heterocyclic derivative 杨森科学爱尔兰无限公司 2024-04-12 CN disclosed
CN-117715909-A Condensed heterocyclic derivative 杨森科学爱尔兰无限公司 2024-03-15 CN disclosed
CN-116438171-A Substituted pyridine derivatives as SARM1 inhibitors 努拉生物公司 2023-07-14 CN disclosed
CN-111372936-B Mcl-1 selective inhibitors, their preparation and use 北京赛林泰医药技术有限公司 2022-12-02 CN disclosed