Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL298871 | 0.85 | SMN1; SMN2 (0.37) | SMN1; SMN2APOBEC3AAPOBEC3GAKR1C3AKR1C1 | |
| SCHEMBL29052704 | 0.84 | ALDH1A1 (0.32) | SMN1; SMN2ALOX15F2PLAUELANE | |
| SCHEMBL10026473 | 0.77 | MME (0.39) | SMN1; SMN2AKR1C3AKR1C1KDM4EALOX15 | |
| SCHEMBL29005126 | 0.76 | CYP1A2 (0.45) | SMN1; SMN2KDM4ETSHRPOLB | |
| SCHEMBL18158115 | 0.74 | SMN1; SMN2 (0.39) | SMN1; SMN2APOBEC3AAPOBEC3GAKR1C3AKR1C1 | |
| SCHEMBL17489082 | 0.73 | SMN1; SMN2 (0.38) | SMN1; SMN2AKR1C3AKR1C1KDM4EALOX15 | |
| SCHEMBL28960941 | 0.71 | P2RX7 (0.32) | — | |
| SCHEMBL29224204 | 0.70 | NOTUM (0.35) | — | |
| SCHEMBL17853366 | 0.70 | MME (0.43) | SMN1; SMN2AKR1C3AKR1C1KDM4EALOX15 | |
| SCHEMBL22125628 | 0.70 | MME (0.35) | SMN1; SMN2AKR1C3AKR1C1KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528864-A | Heteroaryl carboxamide compounds | 安斯泰来制药株式会社 | 2023-08-01 | — | — | CN | disclosed |
| CN-116134018-A | 2-oxoimidazolidine-4-carboxamide as NAV1.8 inhibitor | 默沙东有限责任公司 | 2023-05-16 | — | — | CN | disclosed |