Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.77 |
| ▸ | ACHE | P22303 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| O-Xylene SCHEMBL11035539 | 0.88 | TSHR (1.00) | TSHRACHEALDH1A1CA1CA2 | |
| O-Xylene SCHEMBL11033471 | 0.88 | TSHR (1.00) | TSHRACHEALDH1A1CA1CA2 | |
| O-Xylene SCHEMBL8216257 | 0.88 | TSHR (1.00) | TSHRACHEALDH1A1CA1CA2 | |
| O-Xylene SCHEMBL772 | 0.88 | — | — | |
| O-Xylene SCHEMBL11034038 | 0.88 | TSHR (1.00) | TSHRACHEALDH1A1CA1CA2 | |
| O-Xylene SCHEMBL29385454 | 0.88 | — | — | |
| O-Xylene SCHEMBL2854068 | 0.88 | — | — | |
| O-Xylene SCHEMBL10522915 | 0.88 | TSHR (1.00) | TSHRACHEALDH1A1CA1CA2 | |
| O-Xylene SCHEMBL170581 | 0.88 | TSHR (1.00) | TSHRACHEALDH1A1CA1CA2 | |
| O-Xylene SCHEMBL6898695 | 0.88 | TSHR (1.00) | TSHRACHEALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120116093-A1 | ONE POT PROCESS FOR PREPARING 2-BUTYL-3-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,3-DIAZASPIRO [4, 4] NON-1-EN-4-ONE (IRBESARTAN) | CTX Life Sciences Pvt. Ltd (IN) | 2012-05-10 | — | — | US | claimed |
| EP-2417110-A2 | A ONE POT PROCESS FOR PREPARING 2-BUTYL-3-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,3-DIAZASPIRO [4, 4]NON-1-EN-4-ONE (IRBESARTAN) | CTX Life Sciences Pvt. Ltd. (IN) | 2012-02-15 | — | — | EP | claimed |
| WO-2010116380-A2 | A ONE POT PROCESS FOR PREPARING 2-BUTYL-3-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,3-DIAZASPIRO [4, 4] NON-1-EN-4-ONE (IRBESARTAN) | CTX LIFE SCIENCES PVT. LTD. (IN) | 2010-10-14 | — | — | WO | claimed |
| EP-1135437-B1 | LOW DUST BALANCED HARDNESS ANTIOXIDANT AGGLOMERATES AND PROCESS FOR THE PRODUCTION OF SAME | ALBEMARLE CORP (US) | 2004-06-30 | — | — | EP | claimed |
| EP-1115784-A1 | LOW DUST BALANCED HARDNESS ANTIOXIDANT PELLETS AND PROCESS FOR THE PRODUCTION OF SAME | ALBEMARLE CORPORATION (US) | 2001-07-18 | — | — | EP | claimed |
| US-6056898-A | Low dust balanced hardness antioxidant pellets and process for the production of same | ALBEMARLE CORPORATION (US) | 2000-05-02 | — | — | US | claimed |
| WO-2000017267-A1 | LOW DUST BALANCED HARDNESS ANTIOXIDANT PELLETS AND PROCESS FOR THE PRODUCTION OF SAME | ALBEMARLE CORPORATION (US) | 2000-03-30 | — | — | WO | claimed |
| CN-115260494-B | Polyimide and thin-layer composite film thereof and preparation method | 中国科学院长春应用化学研究所 | 2024-03-01 | — | — | CN | disclosed |
| CN-111225907-B | Process for preparing benzothien-2 yl boric acid/borate | 拜耳制药股份公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-115260494-A | Polyimide, thin-layer composite film thereof and preparation method | 中国科学院长春应用化学研究所 | 2022-11-01 | — | — | CN | disclosed |
| EP-2427269-B1 | IMPROVEMENTS RELATING TO HYDROGENATION OF AROMATICS AND OTHER UNSATURATED ORGANIC COMPOUNDS | SHELL INT RESEARCH (NL) | 2020-06-17 | — | — | EP | disclosed |
| CN-111225907-A | Process for preparing benzothien-2-yl boronic acids/borates | 拜耳制药股份公司 | 2020-06-02 | — | — | CN | disclosed |
| US-10167365-B2 | Polymer and composition | DSM IP ASSETS B.V. (NL) | 2019-01-01 | — | — | US | disclosed |
| EP-1115784-A1 | LOW DUST BALANCED HARDNESS ANTIOXIDANT PELLETS AND PROCESS FOR THE PRODUCTION OF SAME | ALBEMARLE CORPORATION (US) | 2001-07-18 | — | — | EP | disclosed |
| US-6056898-A | Low dust balanced hardness antioxidant pellets and process for the production of same | ALBEMARLE CORPORATION (US) | 2000-05-02 | — | — | US | disclosed |
| WO-2000017267-A1 | LOW DUST BALANCED HARDNESS ANTIOXIDANT PELLETS AND PROCESS FOR THE PRODUCTION OF SAME | ALBEMARLE CORPORATION (US) | 2000-03-30 | — | — | WO | disclosed |
| EP-0433148-B1 | Process for making a metallic deposition on a carbon substrate and mirror obtained by this process | ONERA (OFF NAT AEROSPATIALE) (FR) | 1994-04-06 | — | — | EP | disclosed |
| EP-0433148-A1 | Process for making a metallic deposition on a carbon substrate and mirror obtained by this process | Office National d'Etudes et de Recherches Aérospatiales (O.N.E.R.A.) (FR) | 1991-06-19 | — | — | EP | disclosed |
| US-4990613-A | Bactericides | LEDERLE (JAPAN), LTD. (JP) | 1991-02-05 | — | — | US | disclosed |
| US-4226765-A | Novel rifamycin compounds of high antibiotic activity | ARCHIFAR INDUSTRIE CHIMICHE DEL TRENTINO S.P.A. (IT) | 1980-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120116093-A1 | ONE POT PROCESS FOR PREPARING 2-BUTYL-3-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,3-DIAZASPIRO [4, 4] NON-1-EN-4-ONE (IRBESARTAN) | PKD1, AGTR1, NPR1 | TSHR 29/4885ACHE 4453/4885ALDH1A1 1302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.