Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30273394 | 1.00 | CES2 (0.42) | CES2CES1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29878157 | 0.76 | CES2 (0.42) | CES2CES1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29877750 | 0.76 | CES2 (0.42) | CES2CES1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL24364780 | 0.72 | ESR2 (0.36) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30470897 | 0.72 | ESR2 (0.36) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30390296 | 0.72 | RAB9A (0.57) | ALDH1A1MAPTSMN1; SMN2POLBTSHR | |
| SCHEMBL5609313 | 0.71 | CES2 (0.58) | CES2CES1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL117205 | 0.71 | GAA (0.56) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL761929 | 0.70 | SMN1; SMN2 (0.57) | ALDH1A1MAPTSMN1; SMN2POLBTSHR | |
| SCHEMBL25414765 | 0.70 | ALDH1A1 (0.38) | CES2CES1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115724791-A | Preparation method of 2-methyl-3-nitro-5-aminopyridine | 安徽金禾化学材料研究所有限公司 | 2023-03-03 | — | — | CN | claimed |
| CN-115724791-A | Preparation method of 2-methyl-3-nitro-5-aminopyridine | 安徽金禾化学材料研究所有限公司 | 2023-03-03 | — | — | CN | disclosed |
| CN-115724791-A | Preparation method of 2-methyl-3-nitro-5-aminopyridine | 安徽金禾化学材料研究所有限公司 | 2023-03-03 | — | — | CN | disclosed |