SCHEMBL28964183

SCHEMBL28964183

COc1cc(OC)c2cc(C(=O)O)cc(O)c2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.57
TPMT P51580 6/20 0.54
CA1 P00915 4/20 0.51
CA2 P00918 4/20 0.51
CA12 O43570 3/20 0.51
CA4 P22748 3/20 0.51
CA6 P23280 3/20 0.51
CA7 P43166 3/20 0.51
CA9 Q16790 3/20 0.51
CA14 Q9ULX7 3/20 0.51
PKM P14618 2/20 0.51
CA3 P07451 2/20 0.51
CA5A P35218 2/20 0.51
CA5B Q9Y2D0 2/20 0.51
LMNA P02545 2/20 0.48
HTT P42858 1/20 0.47
MAPK1 P28482 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
USP2 O75604 1/20 0.46
CYP3A4 P08684 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7568873 0.86 XDH (0.51) PTGS2TPMTCA1CA2CA12
SCHEMBL28857298 0.80 CA1 (0.69) PTGS2TPMTCA1CA2CA12
SCHEMBL6959377 0.77 PTGS2 (0.57) PTGS2TPMTCA1CA2CA12
SCHEMBL28071758 0.76 CA12 (0.67) PTGS2TPMTCA1CA2CA12
SCHEMBL28857372 0.76 CA12 (0.63) PTGS2TPMTCA1CA2CA12
SCHEMBL29771941 0.76 CA12 (0.63) PTGS2TPMTCA1CA2CA12
SCHEMBL5069079 0.76 CYP3A4 (0.45) CA1CA2CA12CA7CA9
SCHEMBL3776039 0.75 TPMT (0.64) PTGS2TPMTCA1CA2CA12
SCHEMBL12193496 0.74 KDM4E (0.65) PTGS2TPMTCA1CA2LMNA
SCHEMBL30615314 0.73 PTGS2 (1.00) PTGS2TPMTCA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115490577-A Preparation method and application of 5, 7-dimethoxy-1-naphthol 阜阳欣奕华制药科技有限公司 2022-12-20 CN claimed
CN-115490577-A Preparation method and application of 5, 7-dimethoxy-1-naphthol 阜阳欣奕华制药科技有限公司 2022-12-20 CN disclosed
CN-115490577-A Preparation method and application of 5, 7-dimethoxy-1-naphthol 阜阳欣奕华制药科技有限公司 2022-12-20 CN disclosed