Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28964183 | 0.86 | PTGS2 (0.57) | KDM4ELMNAFUT7TDP1CYP3A4 | |
| SCHEMBL30076482 | 0.82 | SMN1; SMN2 (0.48) | POLBCNR2CYP3A4USP2MAPK1 | |
| SCHEMBL7574341 | 0.82 | SMN1; SMN2 (0.48) | POLBCNR2CYP3A4USP2MAPK1 | |
| SCHEMBL7789713 | 0.79 | FTO (0.53) | XDHKDM4EPOLBGAALMNA | |
| SCHEMBL6043174 | 0.78 | FTO (0.52) | XDHKDM4EPOLBGAALMNA | |
| SCHEMBL1844411 | 0.75 | LCK (0.55) | XDHKDM4EPOLBGAALMNA | |
| SCHEMBL5069079 | 0.75 | CYP3A4 (0.45) | KDM4EPOLBGAAL3MBTL1CYP3A4 | |
| SCHEMBL30594704 | 0.74 | KDM4E (0.77) | XDHKDM4EPOLBGAALMNA | |
| SCHEMBL1465618 | 0.74 | KDM4E (0.77) | XDHKDM4EPOLBGAALMNA | |
| SCHEMBL6132065 | 0.74 | PTPN11 (0.58) | XDHKDM4EPOLBGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984929-B1 | NAPHTHOPYRAN DERIVATIVES, COMPOSITIONS AND (CO)POLYMER MATRICES CONTAINING THE SAME | CORNING SA (FR) | 2002-09-11 | — | — | EP | disclosed |
| US-6399791-B1 | PHOTOCHROMISM | CORNING S.A. (FR) | 2002-06-04 | — | — | US | disclosed |
| CN-1250438-A | Naphthopyran derivatives, compositions and polymer matrices containing them | CORNING INC (US) | 2000-04-12 | — | — | CN | disclosed |
| EP-0984929-A1 | NAPHTHOPYRAN DERIVATIVES, COMPOSITIONS AND (CO)POLYMERS MATRICES CONTAINING SAME | CORNING INCORPORATED (US) | 2000-03-15 | — | — | EP | disclosed |
| EP-0984929-A4 | NAPHTHOPYRAN DERIVATIVES, COMPOSITIONS AND (CO)POLYMERS MATRICES CONTAINING SAME | CORNING INC (US) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998042663-A1 | NAPHTHOPYRAN DERIVATIVES, COMPOSITIONS AND (CO)POLYMERS MATRICES CONTAINING SAME | CORNING INCORPORATED (US) | 1998-10-01 | — | — | WO | disclosed |