Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MYD88 | Q99836 | 1/20 | 0.55 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30205653 | 1.00 | KMT2A (0.67) | KMT2AMEN1PABPC1HTTALDH1A1 | |
| SCHEMBL6677229 | 0.82 | VCAM1 (0.60) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL6678848 | 0.80 | LMNA (0.67) | KMT2AMEN1HTTALDH1A1LMNA | |
| SCHEMBL28746841 | 0.79 | ALDH1A1 (0.60) | ALDH1A1LMNAHPGDVCAM1SMN1; SMN2 | |
| SCHEMBL15544374 | 0.78 | MEN1 (0.62) | KMT2AMEN1PABPC1HTTALDH1A1 | |
| SCHEMBL5225915 | 0.78 | VCAM1 (0.64) | HTTALDH1A1LMNAMAPTVCAM1 | |
| SCHEMBL5228187 | 0.78 | VCAM1 (0.64) | KMT2AMEN1HTTLMNAMAPT | |
| SCHEMBL6675755 | 0.77 | ALDH1A1 (0.64) | KMT2AMEN1HTTALDH1A1LMNA | |
| SCHEMBL6681330 | 0.77 | ALDH1A1 (0.59) | KMT2AMEN1HTTALDH1A1LMNA | |
| SCHEMBL27793353 | 0.77 | VCAM1 (0.54) | HTTALDH1A1LMNAVCAM1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115710251-B | Medullary differentiation factor 88 inhibitor and preparation method and application thereof | 杭州医学院 | 2024-05-28 | — | — | CN | disclosed |
| CN-115710251-A | Myeloid differentiation factor 88 inhibitor and preparation method and application thereof | 杭州医学院 | 2023-02-24 | — | — | CN | disclosed |