Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | PTAFR | P25105 | 10/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4095527 | 0.84 | HRH1 (0.49) | HRH1CHRM2HTR1ACHRM1DRD2 | |
| SCHEMBL4912110 | 0.75 | TSHR (0.43) | HRH1CHRM2HTR1ACHRM1DRD2 | |
| SCHEMBL31317931 | 0.74 | HRH1 (0.58) | HRH1CHRM2HTR1ACHRM1DRD2 | |
| SCHEMBL730635 | 0.74 | HRH1 (0.58) | HRH1CHRM2HTR1ACHRM1DRD2 | |
| SCHEMBL2456241 | 0.74 | TDP2 (0.45) | HRH1CHRM2HTR1ACHRM1DRD2 | |
| SCHEMBL29439737 | 0.74 | TDP2 (0.45) | HRH1CHRM2HTR1ACHRM1DRD2 | |
| SCHEMBL10196364 | 0.74 | HRH1 (0.42) | HRH1CHRM2HTR1ACHRM1DRD2 | |
| SCHEMBL10159247 | 0.74 | PTAFR (0.43) | HRH1CHRM2HTR1ACHRM1DRD2 | |
| SCHEMBL31041390 | 0.74 | LMNA (0.44) | HRH1CHRM2HTR1ACHRM1DRD2 | |
| SCHEMBL16550205 | 0.74 | HRH1 (0.36) | HRH1CHRM2HTR1ACHRM1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551841-A | Azetidin-3-ylcarbinol derivatives as modulators of the CCR6 receptor | 爱杜西亚药品有限公司 | 2022-12-30 | — | — | CN | disclosed |