SCHEMBL730635

SCHEMBL730635

c1ccc2c(c1)CCc1cccnc1-2

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.58
CHRM2 P08172 1/20 0.58
HTR1A P08908 1/20 0.58
CHRM1 P11229 1/20 0.58
DRD2 P14416 1/20 0.58
HTR2A P28223 1/20 0.58
HTR2C P28335 1/20 0.58
ADRA1A P35348 1/20 0.58
OPRK1 P41145 1/20 0.58
HTR2B P41595 1/20 0.58
KCNH2 Q12809 1/20 0.58
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
POLB P06746 1/20 0.50
PTAFR P25105 1/20 0.50
DYRK1A Q13627 1/20 0.49
MIF P14174 1/20 0.47
CES1 P23141 2/20 0.46
CYP19A1 P11511 4/20 0.46
CYP11B2 P19099 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31317931 1.00 HRH1 (0.58) HRH1CHRM2HTR1ACHRM1DRD2
SCHEMBL3900928 0.92 NPY5R (0.53) HRH1CHRM2HTR1ACHRM1DRD2
SCHEMBL28722279 0.92 TSHR (0.52) HRH1CHRM2HTR1ACHRM1DRD2
SCHEMBL22179184 0.84 HRH1 (0.53) HRH1CHRM2HTR1ACHRM1DRD2
SCHEMBL7255792 0.84 CES1 (0.61) HRH1CHRM2HTR1ACHRM1DRD2
SCHEMBL4155420 0.84 HRH1 (0.49) HRH1CHRM2HTR1ACHRM1DRD2
SCHEMBL4155423 0.84 HRH1 (0.49) HRH1CHRM2HTR1ACHRM1DRD2
SCHEMBL4095527 0.84 HRH1 (0.49) HRH1CHRM2HTR1ACHRM1DRD2
SCHEMBL4361367 0.83 HRH1 (0.47) HRH1CHRM2HTR1ACHRM1DRD2
SCHEMBL69894 0.83 MEN1 (0.47) HRH1CHRM2HTR1ACHRM1DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859492-B1 ELECTROLUMINESCENT DEVICE WITH IRIDIUM COMPLEX PHILIPS INTELLECTUAL PROPERTY (DE) 2010-08-11 EP claimed
US-20080203028-A1 Electroluminescent Device with Iridium Complex KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) 2008-08-28 US claimed
US-11829036-B2 Optically anisotropic multilayer product and method for producing same ZEON CORPORATION (JP) 2023-11-28 US disclosed
US-11829036-B2 Optically anisotropic multilayer product and method for producing same ZEON CORPORATION (JP) 2023-11-28 US disclosed
EP-3855519-A2 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS Universal Display Corporation (US) 2021-07-28 EP disclosed
EP-3428986-B1 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2021-01-20 EP disclosed
EP-3328872-B1 ELECTROLUMINESCENT BRIDGED METAL COMPLEXES FOR USE IN ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-05-29 EP disclosed
EP-3428986-A1 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS Universal Display Corporation (US) 2019-01-16 EP disclosed
US-20180362565-A1 METHOD FOR PRODUCING CYCLOMETALATED IRIDIUM COMPLEX TANAKA KIKINZOKU KOGYO K.K. (JP) 2018-12-20 US disclosed
EP-1763902-B1 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2018-08-29 EP disclosed
US-10053479-B2 Raw material and production method for cyclometalated iridium complex TANAKA KIKINZOKU KOGYO K.K. (JP) 2018-08-21 US disclosed
WO-2006090301-A1 ELECTROLUMINESCENT DEVICE WITH IRIDIUM COMPLEX PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH (DE) 2006-08-31 WO disclosed
US-7078115-B2 Metal coordination compound and electroluminescence device CANON KABUSHIKI KAISHA (JP) 2006-07-18 US disclosed
WO-2006014599-A2 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2006-02-09 WO disclosed
US-20060008673-A1 Electroluminescent efficiency THE UNIVERSITY OF SOUTHERN CALIFORNIA 2006-01-12 US disclosed
US-20050085654-A1 Metal coordination compound and electroluminescence device CANON KABUSHIKI KAISHA (JP) 2005-04-21 US disclosed
US-6824894-B2 RETAINS HIGH LUMINANCE OR BRIGHTNESS FOR A LONG PERIOD AND EXHIBITING A STABILITY CANON KABUSHIKI KAISHA (JP) 2004-11-30 US disclosed
CN-1503785-A Metal coordination compound and electroluminescence device ������������ʽ���� 2004-06-09 CN disclosed
EP-1400514-A1 METAL COORDINATION COMPOUND AND ELECTROLUMINESCENCE DEVICE CANON KABUSHIKI KAISHA (JP) 2004-03-24 EP disclosed
US-20030235712-A1 Metal coordination compound and electroluminescence device CANON KABUSHIKI KAISHA (JP) 2003-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080203028-A1 Electroluminescent Device with Iridium Complex TBL3, TBC1D5, TBL2 HRH1 170/4885CHRM2 198/4885HTR1A 3512/4885
US-20180362565-A1 METHOD FOR PRODUCING CYCLOMETALATED IRIDIUM COMPLEX PRKCA, PRKACG, PRKACB HRH1 92/4885CHRM2 731/4885HTR1A 3103/4885
US-20050085654-A1 Metal coordination compound and electroluminescence device MCOLN1, L1CAM, AP1M1 HRH1 737/4885CHRM2 121/4885HTR1A 1660/4885
US-20060008673-A1 Electroluminescent efficiency EML4, LEF1, ESR1 HRH1 2889/4885CHRM2 970/4885HTR1A 3354/4885
US-10053479-B2 Raw material and production method for cyclometalated iridium complex DTYMK, IPO5, IPMK HRH1 1820/4885CHRM2 4218/4885HTR1A 4143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.