Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4364196 | 0.81 | POLB (0.53) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8509314 | 0.80 | ALDH1A1 (0.56) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28226450 | 0.79 | POLB (0.50) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3192618 | 0.79 | POLB (0.50) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7836270 | 0.79 | MAPT (0.54) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL391701 | 0.77 | POLB (0.58) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1800895 | 0.77 | POLB (0.61) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9068980 | 0.77 | POLB (0.61) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8530976 | 0.76 | MAPT (0.56) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10408623 | 0.75 | MEN1 (0.46) | POLBMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191674-A | A kind of synthetic method of benzidine compound | 邵玉田 | 2018-06-22 | — | — | CN | disclosed |