SCHEMBL8530976

SCHEMBL8530976

CC(=O)C(C(=O)Nc1ccccc1)[N+](=O)[O-]

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.56
ALDH1A1 P00352 5/20 0.56
LMNA P02545 2/20 0.56
GAA P10253 1/20 0.56
ATM Q13315 1/20 0.56
CYP1A2 P05177 1/20 0.50
CYP2C19 P33261 1/20 0.50
NAPRT Q6XQN6 1/20 0.48
HSD17B10 Q99714 1/20 0.48
KMT2A Q03164 4/20 0.47
MEN1 O00255 3/20 0.47
RXFP1 Q9HBX9 1/20 0.47
POLB P06746 3/20 0.47
MME P08473 1/20 0.45
ACE P12821 1/20 0.45
HSP90AA1 P07900 1/20 0.45
GPR55 Q9Y2T6 1/20 0.45
HPGD P15428 1/20 0.44
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8509314 0.81 ALDH1A1 (0.56) MAPTALDH1A1LMNAGAAATM
SCHEMBL9846364 0.80 MAPT (0.45) MAPTALDH1A1LMNAGAAATM
SCHEMBL7760594 0.80 MAPT (0.44) MAPTALDH1A1LMNAGAAATM
SCHEMBL8752414 0.79 MAPT (0.48) MAPTALDH1A1LMNAGAAATM
SCHEMBL4364196 0.79 POLB (0.53) MAPTALDH1A1LMNAGAAATM
SCHEMBL27798630 0.77 ALDH1A1 (0.51) MAPTALDH1A1LMNAGAAATM
SCHEMBL3192618 0.76 POLB (0.50) MAPTALDH1A1LMNAGAAATM
SCHEMBL28965007 0.76 POLB (0.50) MAPTALDH1A1LMNAGAAATM
SCHEMBL28226450 0.76 POLB (0.50) MAPTALDH1A1LMNAGAAATM
SCHEMBL7836270 0.76 MAPT (0.54) MAPTALDH1A1LMNAGAAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-214915972-U Reaction kettle for p-chloro-o-nitro acetoacetanilide 湖北丰杯生物科技有限公司 2021-11-30 CN claimed
CN-113683526-B Method for preparing p-chloro-o-nitroacetanilide by using packed bed reactor 山东京博农化科技股份有限公司 2023-06-30 CN disclosed
CN-214915972-U Reaction kettle for p-chloro-o-nitro acetoacetanilide 湖北丰杯生物科技有限公司 2021-11-30 CN disclosed
EP-0295797-B1 Process for the selective reduction of 2-quinoxalinol-4-oxides to 2-quinoxalinols UNIROYAL CHEM CO INC (US) 1998-01-07 EP disclosed
CN-1017994-B Process for producing 2-quinoxalinol UNIROYAL CHEM CO INC (US) 1992-08-26 CN disclosed
CN-1017995-B Process for the selective reduction of 2-quinoxalinol-4-oxides UNIROYAL CHEM CO INC (US) 1992-08-26 CN disclosed
US-4814444-A SULFIDED PLATINUM, SULFIDED PALLADIUM, OR SULFIDED RHODIUM REDUCING CATALYSTS UNIROYAL CHEMICAL COMPANY, INC. (US) 1989-03-21 US disclosed
CN-1030914-A The production method of 2-quinoxaline UNIROYAL CHEM CO INC (US) 1989-02-08 CN disclosed
CN-1030915-A The process for selective reduction of 2-quinoxaline-4-oxide compound UNIROYAL CHEM CO INC (US) 1989-02-08 CN disclosed
EP-0295797-A2 Process for the selective reduction of 2-quinoxaline-4-oxides UNIROYAL CHEMICAL COMPANY, Inc. (US) 1988-12-21 EP disclosed
US-4636562-A Process for preparing 6-halo-2-chloroquinoxaline E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-01-13 US disclosed
US-4305833-A Lubricating oils containing acetoacetanilides as antioxidants UOP INC. (US) 1981-12-15 US disclosed