SCHEMBL28965374

SCHEMBL28965374

CCC(=O)OCCOC(=O)COC(=O)C(C)O

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.44
DGKA P23743 1/20 0.35
GAA P10253 1/20 0.35
HTT P42858 1/20 0.33
KDM4E B2RXH2 1/20 0.33
HIF1A Q16665 2/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
HPGD P15428 1/20 0.32
CYP2C19 P33261 1/20 0.32
BLM P54132 1/20 0.32
WRN Q14191 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ALOX15 P16050 1/20 0.31
MAPT P10636 1/20 0.31
NLRP3 Q96P20 1/20 0.30
DNM1 Q05193 1/20 0.30
ESR1 P03372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10015706 0.92 DGKA (0.35) NAAADGKACYP2C19BLMTDP1
SCHEMBL28965377 0.90 NAAA (0.36) NAAAGAAHIF1AALDH1A1CYP1A2
SCHEMBL13226995 0.84 TSHR (0.36) DGKATDP1
SCHEMBL28965388 0.83 ALDH1A1 (0.36) NAAAGAAHIF1AALDH1A1CYP1A2
SCHEMBL2600802 0.83 NAAA (0.54) NAAADGKAGAAHTTKDM4E
SCHEMBL2600803 0.83 NAAA (0.54) NAAADGKAGAAHTTKDM4E
SCHEMBL9311859 0.82 NAAA (0.47) NAAADGKAALDH1A1HPGDTDP1
SCHEMBL14586209 0.82 TSHR (0.34) ALDH1A1TDP1
SCHEMBL2874396 0.81 MGAM (0.48) GAAALDH1A1CYP1A2ALOX15NLRP3
SCHEMBL14008309 0.81 TDP1 (0.30) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115745946-B Low-temperature preparation method of glycolide and lactide 中国科学院长春应用化学研究所 2024-03-26 CN disclosed
CN-115650948-B Preparation method of glycolide-lactide 中国科学院长春应用化学研究所 2023-12-19 CN disclosed
CN-115745946-A Low-temperature preparation method of glycolide-lactide 中国科学院长春应用化学研究所 2023-03-07 CN disclosed
CN-115650948-A Preparation method of glycolide-lactide 中国科学院长春应用化学研究所 2023-01-31 CN disclosed