Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28965428 | 0.91 | LMNA (0.34) | LMNAHKDC1TRPA1TSHRHTR2A | |
| SCHEMBL4578055 | 0.81 | AOC3 (0.36) | LMNATRPA1HTR2AHRH1POLB | |
| SCHEMBL2832101 | 0.77 | LMNA (0.34) | LMNAHTR2AHRH1 | |
| SCHEMBL5282777 | 0.74 | LMNA (0.45) | LMNAHKDC1TRPA1TSHRHTR2A | |
| SCHEMBL11318850 | 0.71 | KMT2A (0.36) | LMNATRPA1TSHRHTR2ACYP3A4 | |
| SCHEMBL5292306 | 0.69 | LMNA (0.41) | LMNATSHRHTR2AHRH1POLB | |
| SCHEMBL5302177 | 0.69 | TP53 (0.48) | LMNATSHRHTR2AHRH1POLB | |
| SCHEMBL1503494 | 0.69 | LMNA (0.37) | LMNATSHRHTR2AHRH1POLB | |
| SCHEMBL5328939 | 0.68 | CRHBP (0.40) | LMNATRPA1TSHRHTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL1880314 | 0.68 | LMNA (0.36) | LMNATSHRHTR2AHRH1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115745946-A | Low-temperature preparation method of glycolide-lactide | 中国科学院长春应用化学研究所 | 2023-03-07 | — | — | CN | disclosed |