Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.58 |
| ▸ | F2R | P25116 | 3/20 | 0.58 |
| ▸ | KDM1A | O60341 | 9/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.44 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.44 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CHKA | P35790 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27152216 | 0.90 | ITGB3 (0.51) | ITGB3ITGA2BF2RKDM1AMAOA | |
| SCHEMBL20601116 | 0.88 | ALDH1A1 (0.46) | ITGB3ITGA2BF2RTPSAB1TPSD1 | |
| SCHEMBL4678334 | 0.87 | ITGB3 (0.49) | ITGB3ITGA2BF2RKDM1AMAOA | |
| SCHEMBL20298350 | 0.86 | ALDH1A1 (0.49) | ITGB3ITGA2BF2RALDH1A1THRB | |
| SCHEMBL27797265 | 0.86 | ALDH1A1 (0.45) | ITGB3ITGA2BF2RALDH1A1THRB | |
| Hydrochloric Acid SCHEMBL4685471 | 0.85 | ITGB3 (0.48) | ITGB3ITGA2BF2RKDM1AMAOA | |
| SCHEMBL3328785 | 0.84 | ITGB3 (0.46) | ITGB3ITGA2BF2RKDM1AMAOA | |
| Hydrochloric Acid SCHEMBL6150606 | 0.83 | ITGB3 (0.46) | ITGB3ITGA2BF2RKDM1AMAOA | |
| SCHEMBL29233709 | 0.82 | ALDH1A1 (0.43) | ITGB3ITGA2BF2RTPSAB1TPSD1 | |
| Hydrochloric Acid SCHEMBL6152281 | 0.81 | TPSAB1 (0.48) | ITGB3ITGA2BF2RTPSAB1TPSD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605267-A | Selective modulators of mutant LRRK2 proteolysis and related methods of use | 阿维纳斯企业公司（US） | 2023-01-13 | — | — | CN | disclosed |