Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23578236 | 0.85 | SIRT6 (0.41) | SIRT6POLBKDM4ETDP1MAPT | |
| SCHEMBL23577638 | 0.83 | SIRT6 (0.42) | SIRT6POLBKDM4ETDP1MAPT | |
| SCHEMBL29267770 | 0.76 | POLB (0.40) | SIRT6POLBKDM4ETDP1MAPT | |
| SCHEMBL23577603 | 0.75 | MAPT (0.45) | SIRT6POLBKDM4ETDP1MAPT | |
| SCHEMBL23578343 | 0.75 | SIRT6 (0.44) | SIRT6POLBKDM4ETDP1MAPT | |
| SCHEMBL28965638 | 0.74 | KDM4E (0.42) | SIRT6POLBKDM4ETDP1MAPT | |
| SCHEMBL29267748 | 0.74 | ALDH1A1 (0.42) | SIRT6POLBTDP1MAPTRECQL | |
| SCHEMBL30183682 | 0.74 | SIRT6 (0.43) | SIRT6POLBKDM4ETDP1MAPT | |
| SCHEMBL23578549 | 0.72 | SIRT6 (0.40) | SIRT6POLBKDM4ETDP1MAPT | |
| SCHEMBL30183710 | 0.72 | SIRT6 (0.40) | SIRT6POLBKDM4ETDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605476-A | Substituted tricyclic compounds | 鲁宾有限公司（IN） | 2023-01-13 | — | — | CN | disclosed |