Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1408706 | 0.88 | ALDH1A1 (0.48) | TSHRALDH1A1NOTUMSMN1; SMN2MEN1 | |
| SCHEMBL29092593 | 0.84 | SMN1; SMN2 (0.52) | TSHRALDH1A1NOTUMSMN1; SMN2MEN1 | |
| SCHEMBL20869536 | 0.79 | NOTUM (0.53) | TSHRALDH1A1NOTUMSMN1; SMN2MEN1 | |
| SCHEMBL30634122 | 0.78 | SMN1; SMN2 (0.46) | ALDH1A1NOTUMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8861369 | 0.78 | SMN1; SMN2 (0.50) | TSHRALDH1A1NOTUMSMN1; SMN2MEN1 | |
| SCHEMBL12078339 | 0.78 | HTR2C (0.39) | MEN1KMT2ASIGMAR1LMNAMAPT | |
| SCHEMBL6995452 | 0.78 | NOTUM (0.59) | TSHRALDH1A1NOTUMSMN1; SMN2MEN1 | |
| SCHEMBL4983966 | 0.78 | NOTUM (0.47) | TSHRALDH1A1NOTUMSMN1; SMN2MEN1 | |
| SCHEMBL30205876 | 0.75 | CYP2A6 (0.46) | ALDH1A1MEN1KMT2ASIGMAR1MAPT | |
| SCHEMBL4688756 | 0.75 | SMN1; SMN2 (0.56) | TSHRALDH1A1NOTUMSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113651758-B | Synthetic method of benzo-hydrogenated imidazolone framework | 南通大学 | 2023-03-14 | — | — | CN | claimed |
| CN-113651758-B | Synthetic method of benzo-hydrogenated imidazolone framework | 南通大学 | 2023-03-14 | — | — | CN | disclosed |