SCHEMBL1408706

SCHEMBL1408706

CON1CCc2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.48
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
USP2 O75604 1/20 0.48
CDK4 P11802 1/20 0.48
ALOX15 P16050 1/20 0.48
CCND1 P24385 1/20 0.48
SMN1; SMN2 Q16637 4/20 0.47
RAB9A P51151 3/20 0.47
NOTUM Q6P988 2/20 0.47
SIGMAR1 Q99720 1/20 0.46
HPGD P15428 2/20 0.44
NPC1 O15118 2/20 0.44
LMNA P02545 3/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
PTK2B Q14289 1/20 0.43
ESR2 Q92731 1/20 0.43
MAOB P27338 2/20 0.42
TSHR P16473 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28965840 0.88 TSHR (0.50) ALDH1A1KMT2AMEN1SMN1; SMN2NOTUM
SCHEMBL9132803 0.83 ALDH1A1 (0.52) ALDH1A1KMT2AMEN1USP2CDK4
SCHEMBL4685687 0.79 ALDH1A1 (0.48) ALDH1A1KMT2AMEN1USP2CDK4
SCHEMBL12683737 0.79 ALDH1A1 (0.49) ALDH1A1KMT2AMEN1USP2CDK4
SCHEMBL4472565 0.79 ALDH1A1 (0.44) ALDH1A1KMT2AMEN1USP2CDK4
SCHEMBL3899031 0.76 ALDH1A1 (0.46) ALDH1A1KMT2AMEN1USP2CDK4
SCHEMBL14156263 0.76 SMN1; SMN2 (0.46) ALDH1A1KMT2AMEN1USP2CDK4
SCHEMBL6769554 0.76 MEN1 (0.46) ALDH1A1KMT2AMEN1USP2CDK4
SCHEMBL16301363 0.75 ALDH1A1 (0.46) ALDH1A1KMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL8922927 0.73 NOTUM (0.50) ALDH1A1KMT2AMEN1SMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0575604-A1 INDOLINE PRODUCTS, METHODS FOR PREPARING SAME, AND USE THEREOF IN COSMETICS. OREAL (FR) 1993-12-29 EP claimed
WO-1993013744-A1 INDOLINE PRODUCTS, METHODS FOR PREPARING SAME, AND USE THEREOF IN COSMETICS L'OREAL (FR) 1993-07-22 WO claimed
CN-119241548-A Dihydropteridinone derivatives containing fused benzene rings and use thereof 沈阳药科大学 2025-01-03 CN disclosed
US-9650664-B2 Use of photocleavable compounds FEMTONICS KFT (HU) 2017-05-16 US disclosed
WO-2016134450-A1 IMIDAZOPYRIDAZINE AND IMIDAZOTHIADIAZOLE COMPOUNDS Université de Montréal (CA) 2016-09-01 WO disclosed
US-20140234883-A1 USE OF PHOTOCLEAVABLE COMPOUNDS FEMTONICS KFT (HU) 2014-08-21 US disclosed
EP-2763965-A2 USE OF PHOTOCLEAVABLE COMPOUNDS Femtonics Kft. (HU) 2014-08-13 EP disclosed
EP-1034221-B1 DIBENZORHODAMINE DYES USEFUL AS FLUORESCENT LABELLING AGENTS LIFE TECHNOLOGIES CORP (US) 2014-05-14 EP disclosed
WO-2013050798-A2 USE OF PHOTOCLEAVABLE COMPOUNDS FEMTONICS KFT. (HU) 2013-04-11 WO disclosed
WO-2013050795-A1 USE OF PHOTOACTIVE COMPOUNDS FEMTONICS KFT. (HU) 2013-04-11 WO disclosed
EP-2295503-A1 Dibenzorhodamine dyes useful as fluorescent labelling agents Applera Corporation (US) 2011-03-16 EP disclosed
EP-1339798-A2 SULFONATED DIARYLRHODAMINE DYES Applera Corporation (US) 2003-09-03 EP disclosed
US-6583168-B1 Fluorescent labels of nucleosides, nucleotides, polynucleotides, and polypeptides in nucleic acid analysis APPLERA CORPORATION 2003-06-24 US disclosed
WO-2002044416-A2 SULFONATED DIARYLRHODAMINE DYES AS FLUORESCENT LABELS APPLERA CORPORATION (US) 2002-06-06 WO disclosed
EP-1034221-A1 DIBENZORHODAMINE DYES USEFUL AS FLUORESCENT LABELLING AGENTS THE PERKIN-ELMER CORPORATION (US) 2000-09-13 EP disclosed
US-6051719-A FLUORESCENT LABELING REAGENTS THE PERKIN-ELMER CORPORATION (US) 2000-04-18 US disclosed
WO-1999027020-A1 DIBENZORHODAMINE DYES USEFUL AS FLOURESCENT LABELLING AGENTS THE PERKIN-ELMER CORPORATION (US) 1999-06-03 WO disclosed
US-5674876-A ANTIPROLIFERATIVE,-CARCINOGENIC AND -TUMOR AGENTS; SKIN DISORDERS; FREE RADICAL SCAVENGERS RESEARCH DEVELOPMENT FOUNDATION (US) 1997-10-07 US disclosed
WO-1996022089-A1 p-HETEROATOM-SUBSTITUTED PHENOLS AND USES THEREOF RESEARCH DEVELOPMENT FOUNDATION (US) 1996-07-25 WO disclosed
US-5139707-A INDOLINO-SPIROQUINOXALINO OXAZINE PHOTOCHROMATIC COMPOUNDS, METHODS FOR THEIR PREPARATION, PHOTOCHROMIC COMPOSITIONS AND ARTICLES CONTAINING SUCH COMPOUNDS ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 1992-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140234883-A1 USE OF PHOTOCLEAVABLE COMPOUNDS ERCC1, ERCC4, ERCC5 ALDH1A1 2733/4885KMT2A 3176/4885MEN1 782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.