Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4479703 | 0.87 | FOLH1 (0.38) | FOLH1CHRM1TBXA2RADRA1AHTR7 | |
| SCHEMBL20118646 | 0.83 | FOLH1 (0.34) | FOLH1CHRM1TBXA2RADRA1AHTR7 | |
| SCHEMBL10156632 | 0.83 | ALDH1A1 (0.37) | FOLH1CHRM1TBXA2RADRA1AHTR7 | |
| SCHEMBL24326019 | 0.82 | FOLH1 (0.33) | FOLH1CHRM1TBXA2RADRA1AHTR7 | |
| SCHEMBL31161082 | 0.81 | TRPA1 (0.44) | FOLH1CHRM1TBXA2RADRA1AHTR7 | |
| SCHEMBL21791312 | 0.81 | ELANE (0.37) | FOLH1CHRM1TBXA2RADRA1AHTR7 | |
| SCHEMBL15413215 | 0.80 | FOLH1 (0.36) | FOLH1CHRM1TBXA2RADRA1AHTR7 | |
| SCHEMBL22336901 | 0.80 | FOLH1 (0.33) | FOLH1CHRM1TBXA2RADRA1AHTR7 | |
| SCHEMBL10193622 | 0.80 | ALDH1A1 (0.36) | FOLH1CHRM1TBXA2RADRA1AHTR7 | |
| SCHEMBL15413216 | 0.79 | FOLH1 (0.38) | FOLH1CHRM1TBXA2RADRA1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605493-A | Prodrugs of4'-C-substituted-2-halo-2' -deoxyadenosine nucleosides and methods of making and using the same | 吉利德科学公司（US） | 2023-01-13 | — | — | CN | disclosed |