Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28966306 | 0.87 | FOLH1 (0.36) | FOLH1CHRM1TBXA2RADRA1AHTR7 | |
| SCHEMBL20118646 | 0.83 | FOLH1 (0.34) | FOLH1CHRM1TBXA2RADRA1AHTR7 | |
| SCHEMBL10156632 | 0.83 | ALDH1A1 (0.37) | FOLH1CHRM1TBXA2RADRA1AHTR7 | |
| SCHEMBL15413216 | 0.82 | FOLH1 (0.38) | FOLH1CHRM1TBXA2RADRA1AHTR7 | |
| SCHEMBL15413215 | 0.80 | FOLH1 (0.36) | FOLH1CHRM1TBXA2RADRA1AHTR7 | |
| SCHEMBL24326059 | 0.80 | KDM4E (0.35) | FOLH1CHRM1TBXA2RADRA1AHTR7 | |
| SCHEMBL10193622 | 0.80 | ALDH1A1 (0.36) | FOLH1CHRM1TBXA2RADRA1AHTR7 | |
| SCHEMBL24326019 | 0.79 | FOLH1 (0.33) | FOLH1CHRM1TBXA2RADRA1AHTR7 | |
| SCHEMBL23844973 | 0.78 | FOLH1 (0.32) | FOLH1CHRM1TBXA2RADRA1AHTR7 | |
| SCHEMBL8583126 | 0.77 | FOLH1 (0.35) | FOLH1CHRM1TBXA2RADRA1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553989-B2 | Malonic acid monoesters and process for producing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 2009-06-30 | — | — | US | claimed |
| US-20050272950-A1 | Malonic acid monoesters and process for producing the same | MEIJI SEIKA KAISHA LTD. (JP) | 2005-12-08 | — | — | US | claimed |
| EP-1561748-A1 | MALONIC ACID MONOESTERS AND PROCESS FOR PRODUCING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 2005-08-10 | — | — | EP | claimed |
| US-7553989-B2 | Malonic acid monoesters and process for producing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 2009-06-30 | — | — | US | disclosed |
| US-20050272950-A1 | Malonic acid monoesters and process for producing the same | MEIJI SEIKA KAISHA LTD. (JP) | 2005-12-08 | — | — | US | disclosed |
| EP-1561748-A1 | MALONIC ACID MONOESTERS AND PROCESS FOR PRODUCING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 2005-08-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272950-A1 | Malonic acid monoesters and process for producing the same | ME1, SI, ME3 | FOLH1 1196/4885CHRM1 2652/4885TBXA2R 4682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.