Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 7/20 | 0.48 |
| ▸ | METAP1 | P53582 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | CBFB | Q13951 | 11/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28972043 | 1.00 | METAP2 (0.48) | METAP2METAP1NPC1RAB9ALMNA | |
| SCHEMBL28971964 | 1.00 | METAP2 (0.48) | METAP2METAP1NPC1RAB9ALMNA | |
| SCHEMBL28971994 | 1.00 | METAP2 (0.48) | METAP2METAP1NPC1RAB9ALMNA | |
| SCHEMBL28971995 | 1.00 | METAP2 (0.48) | METAP2METAP1NPC1RAB9ALMNA | |
| SCHEMBL30239180 | 0.88 | METAP2 (0.48) | METAP2METAP1NPC1RAB9ALMNA | |
| SCHEMBL28972007 | 0.76 | METAP2 (0.51) | METAP2METAP1NPC1RAB9ALMNA | |
| SCHEMBL27837532 | 0.74 | METAP2 (0.63) | METAP2METAP1NPC1RAB9ALMNA | |
| SCHEMBL2178199 | 0.71 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2HPGDGAA | |
| SCHEMBL9705969 | 0.70 | KDM4E (0.41) | METAP1NPC1RAB9ALMNAPKM | |
| SCHEMBL1896774 | 0.68 | METAP2 (0.48) | METAP2METAP1NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115785161-A | Schiff base iridium complex with aggregation-induced emission effect and preparation and application thereof | 安徽科技学院 | 2023-03-14 | — | — | CN | claimed |
| CN-115819465-A | Alkyl chain modified metal organic iridium complex and preparation method and application thereof | 安徽科技学院 | 2023-03-21 | — | — | CN | disclosed |
| CN-115785161-A | Schiff base iridium complex with aggregation-induced emission effect and preparation and application thereof | 安徽科技学院 | 2023-03-14 | — | — | CN | disclosed |