Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28967459 | 0.86 | MPO (0.42) | MPOSMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL28967457 | 0.85 | MPO (0.39) | MPOPRNPALDH1A1HTTMAPT | |
| SCHEMBL28967452 | 0.85 | RAB9A (0.41) | MPOSMN1; SMN2LMNAHTTMAPT | |
| SCHEMBL28967467 | 0.84 | MPO (0.51) | MPOALDH1A1ATM | |
| SCHEMBL28967480 | 0.84 | MPO (0.44) | MPOELANESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28967465 | 0.80 | MAT2A (0.42) | MPOCA9CA12LMNACYP1A2 | |
| SCHEMBL28967469 | 0.77 | MPO (0.58) | MPOELANESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28967455 | 0.75 | MPO (0.41) | MPOELANECA9SMN1; SMN2LMNA | |
| SCHEMBL28967453 | 0.74 | PTGS1 (0.43) | MPOELANEALDH1A1MAPTATM | |
| SCHEMBL28967458 | 0.74 | ESR2 (0.43) | MPOELANESMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115613060-A | Method for synthesizing C-3 phosphorylated 2H-indazole compound by direct electrochemical oxidation | 浙江工业大学 | 2023-01-17 | — | — | CN | disclosed |