Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.80 |
| ▸ | MEN1 | O00255 | 3/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.80 |
| ▸ | POLB | P06746 | 2/20 | 0.80 |
| ▸ | THRB | P10828 | 1/20 | 0.80 |
| ▸ | HTT | P42858 | 1/20 | 0.80 |
| ▸ | BLM | P54132 | 1/20 | 0.80 |
| ▸ | CBS | P35520 | 1/20 | 0.76 |
| ▸ | XDH | P47989 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.69 |
| ▸ | RECQL | P46063 | 2/20 | 0.69 |
| ▸ | SOST | Q9BQB4 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (-)-Chamaejasmenin B SCHEMBL30226288 | 0.89 | KMT2A (1.00) | MAPTMEN1KMT2APOLBTHRB | |
| SCHEMBL30641793 | 0.89 | CBS (0.67) | MAPTMEN1KMT2APOLBTHRB | |
| SCHEMBL28684198 | 0.89 | CBS (0.67) | MAPTMEN1KMT2APOLBTHRB | |
| (-)-Chamaejasmenin B SCHEMBL28162668 | 0.89 | KMT2A (1.00) | MAPTMEN1KMT2APOLBTHRB | |
| SCHEMBL31190926 | 0.89 | CBS (0.67) | MAPTMEN1KMT2APOLBTHRB | |
| Dihydrokaempferol SCHEMBL3438673 | 0.87 | CYP3A4 (0.80) | MAPTMEN1KMT2APOLBTHRB | |
| Dihydrokaempferol SCHEMBL29367287 | 0.87 | CYP3A4 (0.80) | MAPTMEN1KMT2APOLBTHRB | |
| Dihydrokaempferol SCHEMBL13354175 | 0.87 | CYP3A4 (0.80) | MAPTMEN1KMT2APOLBTHRB | |
| Dihydrokaempferol SCHEMBL39319 | 0.87 | CYP3A4 (0.80) | MAPTMEN1KMT2APOLBTHRB | |
| Dihydrokaempferol SCHEMBL31026899 | 0.87 | CYP3A4 (0.80) | MAPTMEN1KMT2APOLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240315965-A1 | COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS | Natural Extraction Systems, LLC (US) | 2024-09-26 | — | — | US | claimed |
| CN-115969838-A | Application of natural composition as estrogen receptor degradation agent | 三峡大学 | 2023-04-18 | — | — | CN | claimed |
| WO-2022182527-A1 | COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS | Natural Extraction Systems, LLC (US) | 2022-09-01 | — | — | WO | claimed |
| US-12409152-B2 | Compositions and methods related to dissolved oxides | Natural Extraction Systems, LLC (US) | 2025-09-09 | — | — | US | disclosed |
| CN-114377006-B | Absorption promoter for cinnamic acid derivative | 株式会社山田养蜂场本社 | 2024-02-09 | — | — | CN | disclosed |
| CN-115969838-A | Application of natural composition as estrogen receptor degradation agent | 三峡大学 | 2023-04-18 | — | — | CN | disclosed |
| CN-115650941-A | Hesperetin-berberine hydrochloride pharmaceutical co-crystal, and application and preparation method thereof | 广西中医药大学 | 2023-01-31 | — | — | CN | disclosed |
| US-20220362169-A1 | COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES | Natural Extraction Systems, LLC | 2022-11-17 | — | — | US | disclosed |
| US-20220105054-A1 | ABSORPTION ENHANCER OF CINNAMIC ACID DERIVATIVE | YAMADA BEE COMPANY, INC. (JP) | 2022-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12409152-B2 | Compositions and methods related to dissolved oxides | PRKG2, PRKG1, CIT | MAPT 2118/4885MEN1 593/4885KMT2A 3932/4885 |
| US-20220105054-A1 | ABSORPTION ENHANCER OF CINNAMIC ACID DERIVATIVE | FABP2, SLC16A3, SLC16A7 | MAPT 4415/4885MEN1 954/4885KMT2A 1021/4885 |
| US-20220362169-A1 | COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES | PRKG2, PRKG1, CIT | MAPT 2118/4885MEN1 593/4885KMT2A 3932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.