Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 1.00 |
| ▸ | RAB9A | P51151 | 9/20 | 1.00 |
| ▸ | NPC1 | O15118 | 9/20 | 1.00 |
| ▸ | HPGD | P15428 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.64 |
| ▸ | RELA | Q04206 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3584043 | 0.84 | RAB9A (0.81) | SMN1; SMN2RAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL298147 | 0.83 | SMN1; SMN2 (0.75) | SMN1; SMN2RAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL3584407 | 0.81 | SMN1; SMN2 (0.80) | SMN1; SMN2RAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL3582251 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2RAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL3586850 | 0.80 | RAB9A (1.00) | SMN1; SMN2RAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL14877171 | 0.78 | ALDH1A1 (0.75) | SMN1; SMN2RAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL774373 | 0.77 | LCK (0.72) | SMN1; SMN2RAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL4920930 | 0.76 | SMN1; SMN2 (0.78) | SMN1; SMN2RAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL289628 | 0.76 | SMN1; SMN2 (0.63) | SMN1; SMN2RAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL16607174 | 0.75 | ALDH1A1 (0.75) | SMN1; SMN2RAB9ANPC1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |