Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.80 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL656958 | 0.89 | KDM4E (1.00) | KDM4EMEN1KMT2AALDH1A1ACHE | |
| Hydrochloric Acid SCHEMBL6822052 | 0.88 | KDM4E (0.97) | KDM4EMEN1KMT2AALDH1A1ACHE | |
| SCHEMBL19114028 | 0.78 | ALDH1A1 (0.59) | KDM4EALDH1A1ACHEHPGDSRAB9A | |
| SCHEMBL27906338 | 0.78 | KDM4E (0.78) | KDM4ECHEK1MEN1KMT2AALDH1A1 | |
| SCHEMBL23792544 | 0.75 | KDM4E (0.73) | KDM4ECHEK1MEN1KMT2AALDH1A1 | |
| SCHEMBL2691717 | 0.75 | KDM4E (0.73) | KDM4ECHEK1MEN1KMT2AALDH1A1 | |
| SCHEMBL289627 | 0.75 | KDM4E (0.50) | KDM4ECHEK1MEN1KMT2AALDH1A1 | |
| SCHEMBL3065986 | 0.75 | KDM4E (0.73) | KDM4ECHEK1MEN1KMT2ARAB9A | |
| SCHEMBL288846 | 0.74 | KDM4E (0.84) | KDM4EMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL289732 | 0.73 | ALDH1A1 (0.49) | KDM4EMEN1KMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |