SCHEMBL28968802

SCHEMBL28968802

O=C(c1ccccc1)c1ccc2c(n1)C(=O)CCC2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.46
ALDH1A1 P00352 5/20 0.40
KMT2A Q03164 3/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
RAB9A P51151 3/20 0.39
NPC1 O15118 2/20 0.39
TP53 P04637 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
POLB P06746 1/20 0.39
HTT P42858 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
GAA P10253 1/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
CYP2A6 P11509 1/20 0.38
MAOA P21397 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6766148 0.83 ALDH1A1 (0.41) ALDH1A1KMT2AKDM4EMEN1HPGD
SCHEMBL28956536 0.78 BAZ2B (0.38) ALDH1A1KMT2AKDM4EMEN1HPGD
SCHEMBL30694129 0.75 SLC6A15 (0.40) ALDH1A1KDM4EHPGDHSD17B10RAB9A
SCHEMBL883086 0.72 KMT2A (0.53) ALDH1A1KMT2AKDM4EMEN1HPGD
SCHEMBL10286556 0.71 MAOA (0.42) ALDH1A1KMT2AKDM4EMEN1HPGD
SCHEMBL10271343 0.69 KMT2A (0.49) ALDH1A1KMT2AKDM4EMEN1HPGD
SCHEMBL10286485 0.69 KMT2A (0.39) ALDH1A1KMT2AKDM4EMEN1HPGD
SCHEMBL5548270 0.68 ITGB3 (0.40) ALDH1A1KMT2AKDM4EMEN1HPGD
SCHEMBL5604467 0.67 KMT2A (0.63) CNR2ALDH1A1KMT2AKDM4EMEN1
SCHEMBL23376842 0.67 MAOA (0.38) ALDH1A1KMT2AKDM4EMEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115819469-A High-activity transition metal iron complex, preparation method and application thereof 中国科学院化学研究所 2023-03-21 CN disclosed
CN-115385966-A High-activity transition metal cobalt complex, preparation method and application thereof 中国科学院化学研究所 2022-11-25 CN disclosed