Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 7/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25023561 | 1.00 | MEN1 (0.49) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL30306801 | 1.00 | MEN1 (0.49) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL30306884 | 0.87 | GRIA1 (0.47) | RAB9AGRIA1PTPN1 | |
| SCHEMBL28968965 | 0.87 | GRIA1 (0.47) | RAB9AGRIA1PTPN1 | |
| SCHEMBL30306844 | 0.87 | RAB9A (0.46) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL30306748 | 0.85 | TLR2 (0.43) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL25023565 | 0.80 | RAB9A (0.44) | MEN1ALDH1A1HPGDKMT2ARAB9A | |
| SCHEMBL25023560 | 0.79 | RAB9A (0.46) | MEN1ALDH1A1HPGDKMT2ARAB9A | |
| SCHEMBL28968954 | 0.76 | TLR2 (0.47) | KMT2A | |
| SCHEMBL25023379 | 0.76 | TLR2 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115666553-A | TLR2 modulator compounds, and pharmaceutical compositions and uses thereof | 轴向治疗公司 | 2023-01-31 | — | — | CN | disclosed |