Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.42 |
| ▸ | CHRND | Q07001 | 5/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.42 |
| ▸ | CHRNG | P07510 | 1/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30306884 | 1.00 | GRIA1 (0.47) | GRIA1PTPN1LPAR3LPAR1CHRND | |
| SCHEMBL30306801 | 0.87 | MEN1 (0.49) | GRIA1PTPN1RAB9A | |
| SCHEMBL25023561 | 0.87 | MEN1 (0.49) | GRIA1PTPN1RAB9A | |
| SCHEMBL28968969 | 0.87 | MEN1 (0.49) | GRIA1PTPN1RAB9A | |
| SCHEMBL28969006 | 0.85 | RAB9A (0.43) | RAB9A | |
| SCHEMBL28968954 | 0.81 | TLR2 (0.47) | — | |
| SCHEMBL28968992 | 0.80 | TLR2 (0.46) | RAB9A | |
| SCHEMBL28968987 | 0.80 | GRIA1 (0.47) | GRIA1PTPN1LPAR3LPAR1CHRND | |
| SCHEMBL30306849 | 0.80 | GRIA1 (0.47) | GRIA1PTPN1LPAR3LPAR1CHRND | |
| SCHEMBL25023379 | 0.79 | TLR2 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115666553-A | TLR2 modulator compounds, and pharmaceutical compositions and uses thereof | 轴向治疗公司 | 2023-01-31 | — | — | CN | disclosed |