Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 7/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25023561 | 1.00 | MEN1 (0.49) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL28968969 | 1.00 | MEN1 (0.49) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL30306884 | 0.87 | GRIA1 (0.47) | RAB9AGRIA1PTPN1 | |
| SCHEMBL28968965 | 0.87 | GRIA1 (0.47) | RAB9AGRIA1PTPN1 | |
| SCHEMBL30306844 | 0.87 | RAB9A (0.46) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL30306748 | 0.85 | TLR2 (0.43) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL25023565 | 0.80 | RAB9A (0.44) | MEN1ALDH1A1HPGDKMT2ARAB9A | |
| SCHEMBL25023560 | 0.79 | RAB9A (0.46) | MEN1ALDH1A1HPGDKMT2ARAB9A | |
| SCHEMBL28968954 | 0.76 | TLR2 (0.47) | KMT2A | |
| SCHEMBL25023379 | 0.76 | TLR2 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240156780-A1 | TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | AXIAL THERAPEUTICS, INC. (US) | 2024-05-16 | — | — | US | disclosed |
| US-11951094-B2 | TLR2 modulator compounds, pharmaceutical compositions and uses thereof | AXIAL THERAPEUTICS, INC. (US) | 2024-04-09 | — | — | US | disclosed |
| EP-4171547-A1 | TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Axial Therapeutics, Inc. (US) | 2023-05-03 | — | — | EP | disclosed |
| US-20230051773-A1 | TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | AXIAL THERAPEUTICS, INC. (US) | 2023-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230051773-A1 | TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | TLR2, TLR3, TLR4 | MEN1 4682/4885ALDH1A1 4063/4885HPGD 1264/4885 |
| US-20240156780-A1 | TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | TLR2, TLR3, TLR4 | MEN1 4682/4885ALDH1A1 4063/4885HPGD 1264/4885 |
| US-11951094-B2 | TLR2 modulator compounds, pharmaceutical compositions and uses thereof | TLR2, TLR3, TLR4 | MEN1 4682/4885ALDH1A1 4063/4885HPGD 1264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.