Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TACR1 | P25103 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.52 |
| ▸ | ITGAV | P06756 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KYNU | Q16719 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30306792 | 1.00 | MAPT (0.58) | MAPTRAB9ACYP3A4TSHRALDH1A1 | |
| SCHEMBL14609244 | 0.87 | PPARG (0.54) | TACR1ITGB3ITGAVPPARGPPARA | |
| SCHEMBL3370106 | 0.87 | CASP1 (0.53) | MAPTRAB9ATACR1ITGB3ITGAV | |
| SCHEMBL30306824 | 0.86 | MAPT (0.51) | MAPTRAB9ACYP3A4TSHRALDH1A1 | |
| SCHEMBL7407622 | 0.86 | CASP1 (0.53) | MAPTRAB9ATACR1ITGB3ITGAV | |
| SCHEMBL7305160 | 0.85 | ALDH1A1 (0.60) | MAPTCYP3A4TSHRALDH1A1TACR1 | |
| SCHEMBL7370220 | 0.85 | CTSK (0.57) | ALDH1A1TACR1ITGB3ITGAVPPARG | |
| SCHEMBL7370216 | 0.85 | CTSK (0.57) | ALDH1A1TACR1ITGB3ITGAVPPARG | |
| SCHEMBL30306834 | 0.83 | MAPT (0.56) | MAPTRAB9ACYP3A4TSHRALDH1A1 | |
| SCHEMBL7329157 | 0.83 | CTSK (0.58) | TACR1ITGB3ITGAVPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115666553-A | TLR2 modulator compounds, and pharmaceutical compositions and uses thereof | 轴向治疗公司 | 2023-01-31 | — | — | CN | disclosed |