SCHEMBL219477

SCHEMBL219477

CC(=O)Nc1nc2[nH]cnc2c(=O)[nH]1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 1/20 0.62
KDM4E B2RXH2 1/20 0.56
GAA P10253 1/20 0.56
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
TSHR P16473 1/20 0.44
ADORA3 P0DMS8 2/20 0.43
FGFR1 P11362 6/20 0.43
FGFR2 P21802 6/20 0.43
ALDH1A1 P00352 2/20 0.43
POLB P06746 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
ALOX15 P16050 1/20 0.43
LMNA P02545 1/20 0.42
FGFR3 P22607 3/20 0.41
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TAS1R3 Q7RTX0 1/20 0.38
TAS1R1 Q7RTX1 1/20 0.38
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16573451 0.84 SMN1; SMN2 (0.59) GDAKDM4EGAAKMT2AMEN1
SCHEMBL442818 0.84 NOS1 (0.45) GDAKDM4EGAAKMT2AMEN1
SCHEMBL12227604 0.84 GDA (0.45) GDAKDM4EGAAKMT2AMEN1
SCHEMBL12227599 0.83 GDA (0.45) GDAKDM4EGAAKMT2AMEN1
SCHEMBL1398291 0.81 GDA (0.42) GDAKDM4EGAAFGFR1ALDH1A1
SCHEMBL28469810 0.80 GDA (0.42) GDAKDM4EGAAKMT2AMEN1
SCHEMBL28969 0.80 PDPK1 (0.41) GDAKDM4EGAAALDH1A1LMNA
SCHEMBL14260671 0.80 GDA (0.39) GDAKDM4EGAAALDH1A1LMNA
SCHEMBL1425017 0.79 ADORA2A (0.52) KDM4EKMT2AMEN1TSHRADORA3
SCHEMBL12227601 0.77 RAB9A (0.51) KDM4EKMT2AMEN1POLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115367745-B Tungsten-containing substance hybridization and nitrogen-doped porous carbon material and preparation method thereof 北京化工大学 2023-11-24 CN claimed
CN-113149988-B Preparation method and application of ganciclovir 海南锦瑞制药有限公司 2023-04-28 CN claimed
CN-115367726-A Oxygen-doped titanium nitride hybridized and nitrogen-doped porous carbon material and preparation method and application thereof 北京化工大学 2022-11-22 CN claimed
CN-115367745-A Tungsten-containing substance hybrid and nitrogen-doped porous carbon material and preparation method thereof 北京化工大学 2022-11-22 CN claimed
WO-2021238912-A1 TRANSITION METAL COMPOUND-HYBRIDIZED AND NITROGEN-DOPED POROUS CARBON MATERIAL AND PREPARATION METHOD THEREFOR 北京化工大学 2021-12-02 WO claimed
CN-113149988-A Ganciclovir preparation method and application 海南锦瑞制药有限公司 2021-07-23 CN claimed
CN-111892047-A Vanadium nitride hybrid and nitrogen-doped porous carbon material and preparation method and application thereof 北京化工大学 2020-11-06 CN claimed
CN-107074911-B Peptide nucleic acid monomers and oligomers 优基艾森斯股份公司 2020-11-03 CN claimed
US-20090208620-A1 Alimentary Compositions and Methods For Metabolic Modulation VDF FUTURECEUTICALS, INC. (US) 2009-08-20 US claimed
US-20070161582-A1 Pharmaceutical compositions and methods for metabolic modulation VDF FUTURECEUTICALS 2007-07-12 US claimed
WO-2005020892-A2 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR METABOLIC MODULATION MITOCHROMA RESEARCH, INC. (US) 2005-03-10 WO claimed
US-6808716-B2 N-acetylamino acids, related N-acetyl compounds and their topical use YU RUEY J (US) 2004-10-26 US claimed
WO-2004089329-A2 TOPICAL COMPOSITIONS COMPRISING N-ACETYLAMINO ACIDS OR RELATED N-ACETYL COMPOUNDS YU RUEY J (US) 2004-10-21 WO claimed
US-20030198656-A1 N-acetylamino acids, related N-acetyl compounds and their topical use YU RUEY J (US) 2003-10-23 US claimed
US-5780607-A PYRANOSYL NUCLEOSIDE MONOMER UNITS CONNECTED BY AMIDE LINKAGES HOFFMANN-LA ROCHE INC. (US) 1998-07-14 US claimed
WO-1997014709-A1 ANTISENSE OLIGOMERS F. HOFFMANN-LA ROCHE AG (CH) 1997-04-24 WO claimed
CN-1128269-A Oligoribonucleotides with amide backbone HOFFMANN LA ROCHE (CH) 1996-08-07 CN claimed
EP-0714907-A1 Oligoribonucleotides with amide backbone F. HOFFMANN-LA ROCHE AG (CH) 1996-06-05 EP claimed
EP-0049072-A1 Guanine compounds and their use for the preparation of anti-viral agents SYNTEX (U.S.A.) INC. (US) 1982-04-07 EP claimed
US-20260117148-A1 SEMICONDUCTOR TREATMENT LIQUID, TREATMENT METHOD FOR OBJECT TO BE TREATED, AND MANUFACTURING METHOD OF ELECTRONIC DEVICE FUJIFILM CORP (JP) 2026-04-30 US disclosed
EP-3840748-B1 SUBSTITUTED IMIDAZOLES FOR THE INHIBITION OF TGF-BETA AND METHODS OF TREATMENT CLAVIUS PHARMACEUTICALS LLC (US) 2026-04-15 EP disclosed
US-12582656-B2 Nucleotide analogues R.G.C.C. Holdings AG (CH) 2026-03-24 US disclosed
US-20250320430-A1 SEMICONDUCTOR TREATMENT LIQUID, TREATMENT METHOD FOR OBJECT TO BE TREATED, AND MANUFACTURING METHOD OF ELECTRONIC DEVICE FUJIFILM CORP (JP) 2025-10-16 US disclosed
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 US disclosed
EP-4125912-B1 COMPOUNDS FOR THE IN VITRO INHIBITION OF THE RNA-DEPENDENT RNA POLYMERASE OF CORONAVIRUSES R G C C HOLDINGS AG (CH) 2025-07-30 EP disclosed
CN-120309613-A Amplification preparation method of ganciclovir 湖北天义药业有限公司 2025-07-15 CN disclosed
WO-2025134877-A1 KIT AND METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2025-06-26 WO disclosed
US-20250129308-A1 SEMICONDUCTOR TREATMENT LIQUID, TREATMENT METHOD FOR OBJECT TO BE TREATED, AND MANUFACTURING METHOD OF ELECTRONIC DEVICE FUJIFILM CORP (JP) 2025-04-24 US disclosed
CN-119404296-A Semiconductor processing liquid, method for processing object to be processed, and method for manufacturing electronic device 富士胶片株式会社 2025-02-07 CN disclosed
US-20250017209-A1 COMPOSITION, MANUFACTURING METHOD FOR SEMICONDUCTOR ELEMENT, AND CLEANING METHOD FOR SEMICONDUCTOR SUBSTRATE FUJIFILM CORPORATION (JP) 2025-01-16 US disclosed
US-20240400942-A1 CLEANING COMPOSITION AND CLEANING METHOD OF SEMICONDUCTOR SUBSTRATE FUJIFILM CORPORATION (JP) 2024-12-05 US disclosed
CN-118922917-A Composition, method for manufacturing semiconductor element, and method for cleaning semiconductor substrate 富士胶片株式会社 2024-11-08 CN disclosed
US-12077548-B2 Substituted imidazoles for the inhibition of TGF-β and methods of treatment Clavius Pharmaceuticals, LLC. (US) 2024-09-03 US disclosed
WO-2024166627-A1 SEMICONDUCTOR PROCESSING LIQUID, PROCESSING METHOD FOR OBJECT TO BE PROCESSED, AND MANUFACTURING METHOD FOR ELECTRONIC DEVICE 富士フイルム株式会社 2024-08-15 WO disclosed
WO-2024122300-A1 PROCESSING LIQUID, CLEANING METHOD FOR OBJECT TO BE PROCESSED, AND METHOD FOR PRODUCING ELECTRONIC DEVICE 富士フイルム株式会社 2024-06-13 WO disclosed
US-20240117278-A1 TREATMENT LIQUID, CLEANING METHOD OF SEMICONDUCTOR SUBSTRATE, AND MANUFACTURING METHOD OF SEMICONDUCTOR ELEMENT FUJIFILM CORPORATION (JP) 2024-04-11 US disclosed
CN-117551100-A Preparation method of (S) -9- [3- (4, 4' -dimethoxy trityl) -2-hydroxypropyl ] -N2-acetyl guanine 苏州诺维康生物科技有限公司 2024-02-13 CN disclosed
US-20240026254-A1 CLEANING LIQUID FOR SEMICONDUCTOR SUBSTRATE FUJIFILM CORPORATION (JP) 2024-01-25 US disclosed
US-20240018442-A1 CLEANING LIQUID FOR SEMICONDUCTOR SUBSTRATE AND CLEANING METHOD FOR SEMICONDUCTOR SUBSTRATE FUJIFILM CORPORATION (JP) 2024-01-18 US disclosed
WO-2024014224-A1 SEMICONDUCTOR PROCESSING LIQUID, METHOD FOR PROCESSING OBJECT TO BE PROCESSED, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE 富士フイルム株式会社 2024-01-18 WO disclosed
WO-2024014220-A1 SEMICONDUCTOR PROCESSING LIQUID, PROCESSING METHOD FOR OBJECT TO BE PROCESSED, AND MANUFACTURING METHOD FOR ELECTRONIC DEVICE 富士フイルム株式会社 2024-01-18 WO disclosed
CN-115367745-B Tungsten-containing substance hybridization and nitrogen-doped porous carbon material and preparation method thereof 北京化工大学 2023-11-24 CN disclosed
WO-2023182142-A1 COMPOSITION, SEMICONDUCTOR-ELEMENT MANUFACTURING METHOD, AND SEMICONDUCTOR-SUBSTRATE WASHING METHOD 富士フイルム株式会社 2023-09-28 WO disclosed
WO-2023176708-A1 CLEANING COMPOSITION AND SEMICONDUCTOR SUBSTRATE CLEANING METHOD 富士フイルム株式会社 2023-09-21 WO disclosed
CN-113149988-B Preparation method and application of ganciclovir 海南锦瑞制药有限公司 2023-04-28 CN disclosed
CN-113149988-B Preparation method and application of ganciclovir 海南锦瑞制药有限公司 2023-04-28 CN disclosed
US-20230118992-A1 NUCLEOTIDE ANALOGUES R.G.C.C.Holdings AG (CH) 2023-04-20 US disclosed
CN-115819483-A Nucleoside derivatives for treating cancer and use thereof 南京知和医药科技有限公司 2023-03-21 CN disclosed
EP-4125912-A1 NUCLEOTIDE ANALOGUES FOR THE TREATMENT OF CORONAVIRUSES R.G.C.C. Holdings AG (CH) 2023-02-08 EP disclosed
WO-2022255220-A1 PROCESSING SOLUTION, METHOD FOR CLEANING SEMICONDUCTOR SUBSTRATE, AND METHOD FOR MANUFACTURING SEMICONDUCTOR ELEMENT 富士フイルム株式会社 2022-12-08 WO disclosed
CN-115367745-A Tungsten-containing substance hybrid and nitrogen-doped porous carbon material and preparation method thereof 北京化工大学 2022-11-22 CN disclosed
US-11505815-B2 Compositions and methods related to non-templated enzymatic nucleic acid synthesis NUCLERA NUCLEICS, LTD. (GB) 2022-11-22 US disclosed
CN-115367726-A Oxygen-doped titanium nitride hybridized and nitrogen-doped porous carbon material and preparation method and application thereof 北京化工大学 2022-11-22 CN disclosed
WO-2022202287-A1 SEMICONDUCTOR SUBSTRATE CLEANING SOLUTION, AND METHOD FOR CLEANING SEMICONDUCTOR SUBSTRATE 富士フイルム株式会社 2022-09-29 WO disclosed
WO-2022168687-A1 SEMICONDUCTOR SUBSTRATE CLEANING SOLUTION 富士フイルム株式会社 2022-08-11 WO disclosed
US-20220064187-A1 SUBSTITUTED IMIDAZOLES FOR THE INHIBITION OF TGF-BETA AND METHODS OF TREATMENT Clavius Pharmaceuticals, LLC. 2022-03-03 US disclosed
WO-2021238912-A1 TRANSITION METAL COMPOUND-HYBRIDIZED AND NITROGEN-DOPED POROUS CARBON MATERIAL AND PREPARATION METHOD THEREFOR 北京化工大学 2021-12-02 WO disclosed
WO-2021191236-A1 NUCLEOTIDE ANALOGUES FOR THE TREATMENT OF CORONAVIRUSES R.G.C.C. Holdings AG (CH) 2021-09-30 WO disclosed
CN-113149988-A Ganciclovir preparation method and application 海南锦瑞制药有限公司 2021-07-23 CN disclosed
CN-113149988-A Ganciclovir preparation method and application 海南锦瑞制药有限公司 2021-07-23 CN disclosed
CN-108467396-B Ganciclovir preparation method 安徽海康药业有限责任公司 2021-07-20 CN disclosed
EP-3840748-A1 SUBSTITUTED IMIDAZOLES FOR THE INHIBITION OF TGF-BETA AND METHODS OF TREATMENT Clavius Pharmaceuticals, LLC (US) 2021-06-30 EP disclosed
EP-3229610-B1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS INC (US) 2021-06-09 EP disclosed
CN-111892047-A Vanadium nitride hybrid and nitrogen-doped porous carbon material and preparation method and application thereof 北京化工大学 2020-11-06 CN disclosed
CN-107074911-B Peptide nucleic acid monomers and oligomers 优基艾森斯股份公司 2020-11-03 CN disclosed
EP-3710461-A1 NUCLEOTIDE DERIVATIVES CONTAINING AMINE MASKED MOIETIES AND THEIR USE IN A TEMPLATED AND NON-TEMPLATED ENZYMATIC NUCLEIC ACID SYNTHESIS Nuclera Nucleics Ltd (GB) 2020-09-23 EP disclosed
CN-111344296-A Nucleotide derivatives containing amine-masked moieties and their use in templated and non-templated enzymatic nucleic acid synthesis 核酸有限公司 2020-06-26 CN disclosed
EP-2862868-B1 INTERMEDIATE FOR PRODUCTION OF NUCLEOSIDE ANALOGUE, AND METHOD FOR PRODUCING SAME DAIICHI SANKYO CO LTD (JP) 2020-04-08 EP disclosed
WO-2020041562-A1 SUBSTITUTED IMIDAZOLES FOR THE INHIBITION OF TGF-BETA AND METHODS OF TREATMENT CLAVIUS PHARMACEUTICALS, LLC (US) 2020-02-27 WO disclosed
CN-108912122-B Method for synthesizing acyclovir and ganciclovir by carbon-hydrogen bond activation 信阳师范学院 2020-01-07 CN disclosed
US-20190144905-A1 Novel Use Nuclera Nucleics Ltd. (GB) 2019-05-16 US disclosed
WO-2018067973-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2018-04-12 WO disclosed
US-9884885-B2 Synthesis of labile base protected-modified deoxy and modified ribo nucleosides, corresponding phosphoramidites and supports and their use in high purity oligonucleotide synthesis CHEMGENES CORPORATION (US) 2018-02-06 US disclosed
EP-1525209-B1 1'-, 2'- AND 3' -MODIFIED NUCLEOSIDE DERIVATIVES FOR TREATING FLAVIVIRIDAE INFECTIONS IDENIX PHARMACEUTICALS LLC (US) 2017-11-15 EP disclosed
WO-2017192664-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2017-11-09 WO disclosed
US-9738681-B2 Intermediate for production of nucleoside analog and method for producing the same DAIICHI SANKYO COMPANY, LIMITED (JP) 2017-08-22 US disclosed
US-9708357-B2 4′-azido, 3′-fluoro substituted nucleoside derivatives as inhibitors of HCV RNA replication Riboscience, LLC (US) 2017-07-18 US disclosed
US-9708357-B2 4′-azido, 3′-fluoro substituted nucleoside derivatives as inhibitors of HCV RNA replication Riboscience, LLC (US) 2017-07-18 US disclosed
US-9708357-B2 4′-azido, 3′-fluoro substituted nucleoside derivatives as inhibitors of HCV RNA replication Riboscience, LLC (US) 2017-07-18 US disclosed
EP-2794628-B1 4'-AZIDO-3'-FLUORO SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF HCV RNA REPLICATION RIBOSCIENCE LLC (US) 2017-03-29 EP disclosed
US-9408863-B2 5′-substituted nucleoside analogs and methods of use thereof for the treatment of viral diseases MERCK SHARP & DOHME CORP. (US) 2016-08-09 US disclosed
WO-2006102970-A9 MODIFIED SHORT INTERFERING RNA QIAGEN GMBH (DE) 2016-05-26 WO disclosed
US-20160068561-A9 Intermediate for Production of Nucleoside Analog and Method for Producing the Same DAIICHI SANKYO COMPANY, LIMITED (JP) 2016-03-10 US disclosed
EP-1730298-B1 SPECIFIC SUBSTRATES FOR O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE EPFL ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (CH) 2015-11-11 EP disclosed
US-20150152132-A1 Intermediate for Production of Nucleoside Analog and Method for Producing the Same DAIICHI SANKYO COMPANY, LIMITED (JP) 2015-06-04 US disclosed
CN-104610261-A Preparation method of ganciclovir intermediate HUBEI YITAI PHARMACEUTICAL CO LTD 2015-05-13 CN disclosed
EP-2862868-A1 INTERMEDIATE FOR PRODUCTION OF NUCLEOSIDE ANALOGUE, AND METHOD FOR PRODUCING SAME DAIICHI SANKYO COMPANY, LIMITED (JP) 2015-04-22 EP disclosed
US-20140369959-A1 4'-AZIDO, 3'-FLUORO SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF HCV RNA REPLICATION RIBOSCIENCE LLC 2014-12-18 US disclosed
EP-2794628-A1 4'-AZIDO, 3'-FLUORO SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF HCV RNA REPLICATION F.HOFFMANN-LA ROCHE AG (CH) 2014-10-29 EP disclosed
US-8859749-B2 Modified short interfering RNA QIAGEN GMBH (DE) 2014-10-14 US disclosed
US-20140221304-A1 5'-SUBSTITUTED NUCLEOSIDE ANALOGS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES MERCK SHARP & DOHME LLC 2014-08-07 US disclosed
EP-2731433-A1 5'-SUBSTITUTED NUCLEOSIDE ANALOGS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES Merck Sharp & Dohme Corp. (US) 2014-05-21 EP disclosed
US-8569476-B2 Method for preparing oligonucleotide Suzhou Ribo Life Science Co., Ltd. (CN) 2013-10-29 US disclosed
EP-2619215-A1 AZIDO NUCLEOSIDES AND NUCLEOTIDE ANALOGS Alios Biopharma, Inc. (US) 2013-07-31 EP disclosed
WO-2013092447-A1 4'-AZIDO, 3'-FLUORO SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF HCV RNA REPLICATION F. HOFFMANN-LA ROCHE AG (CH) 2013-06-27 WO disclosed
EP-2380896-B1 A METHOD FOR PREPARING OLIGONUCLEOTIDE SUZHOU RIBO LIFE SCIENCE CO LTD (CN) 2013-02-13 EP disclosed
WO-2013009737-A1 5'-SUBSTITUTED NUCLEOSIDE ANALOGS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES MERCK SHARP & DOHME CORP. (US) 2013-01-17 WO disclosed
CN-102702199-A Method for preparing ganciclovir HUBEI GEDIAN RENFU PHARMACEUTICAL CO LTD 2012-10-03 CN disclosed
WO-2012040124-A1 AZIDO NUCLEOSIDES AND NUCLEOTIDE ANALOGS ALIOS BIOPHARMA, INC. (US) 2012-03-29 WO disclosed
US-20120065386-A1 SYNTHESIS OF LABILE BASE PROTECTED - MODIFIED DEOXY & MODIFIED RIBO NUCLEOSIDES, CORRESPONDING PHOSPHORAMIDITES AND SUPPORTS AND THEIR USE IN HIGH PURITY OLIGONUCLEOTIDE SYNTHESIS CHEMGENES CORPORATION 2012-03-15 US disclosed
US-8088752-B2 Methods for metabolic modulation VDF FUTURECEUTICALS, INC. (US) 2012-01-03 US disclosed
EP-2380896-A1 A METHOD FOR PREPARING OLIGONUCLEOTIDE Suzhou Ribo Life Science Co., Ltd (CN) 2011-10-26 EP disclosed
US-20110237786-A1 METHOD FOR PREPARING OLIGONUCLEOTIDE SUZHOU RIBO LIFE SCIENCE CO., LTD (CN) 2011-09-29 US disclosed
US-7662798-B2 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections IDENIX PHARMACEUTICALS, INC. (US) 2010-02-16 US disclosed
US-20090208620-A1 Alimentary Compositions and Methods For Metabolic Modulation VDF FUTURECEUTICALS, INC. (US) 2009-08-20 US disclosed
US-20090208620-A1 Alimentary Compositions and Methods For Metabolic Modulation VDF FUTURECEUTICALS, INC. (US) 2009-08-20 US disclosed
US-20090203638-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR METABOLIC MODULATION VDF FUTURECEUTICALS, INC. (US) 2009-08-13 US disclosed
US-20090197332-A1 Modified Short Interfering RNA QIAGEN GMBH (DE) 2009-08-06 US disclosed
US-20070184067-A1 Alimentary compositions and methods for metabolic modulation VDF FUTURECEUTICALS 2007-08-09 US disclosed
US-20070184067-A1 Alimentary compositions and methods for metabolic modulation VDF FUTURECEUTICALS 2007-08-09 US disclosed
EP-1816135-A1 Production method of fluorinated purine nucleoside derivative, intermediate therefor and production method thereof Ajinomoto Co., Inc. (JP) 2007-08-08 EP disclosed
US-20070179290-A1 Production method of fluorinated purine nucleoside derivative, intermediate therefor and production method thereof AJINOMOTO CO. INC. (JP) 2007-08-02 US disclosed
US-20070161582-A1 Pharmaceutical compositions and methods for metabolic modulation VDF FUTURECEUTICALS 2007-07-12 US disclosed
US-7189849-B2 Synthesis of acyclic nucleoside derivatives MEDIVIR AB (SE) 2007-03-13 US disclosed
WO-2005016268-A3 ALIMENTARY COMPOSITIONS AND METHODS FOR METABOLIC MODULATION MITOCHROMA RES INC (US) 2006-01-05 WO disclosed
US-20050250795-A1 Synthesis of acyclic nucleoside derivatives MEDIVIR AB (SE) 2005-11-10 US disclosed
US-20050171126-A1 Process for the production of purine nucleoside compounds AJINOMOTO CO., INC. (JP) 2005-08-04 US disclosed
EP-1550665-A1 A process for the production of purine nucleoside compounds Ajinomoto Co., Inc. (JP) 2005-07-06 EP disclosed
EP-1535923-A1 Synthesis of acyclic nucleoside derivatives Medivir Aktiebolag (SE) 2005-06-01 EP disclosed
EP-0882050-B2 PROCESS FOR PREPARING PURINE DERIVATIVES HOFFMANN LA ROCHE (CH) 2005-05-04 EP disclosed
EP-1131323-B1 SYNTHESIS OF ACYCLIC NUCLEOSIDE DERIVATIVES MEDIVIR AB (SE) 2005-04-27 EP disclosed
US-6878844-B2 Synthesis of acyclic nucleoside derivatives MEDIVIR AB (SE) 2005-04-12 US disclosed
WO-2005020892-A2 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR METABOLIC MODULATION MITOCHROMA RESEARCH, INC. (US) 2005-03-10 WO disclosed
WO-2005016268-A2 ALIMENTARY COMPOSITIONS AND METHODS FOR METABOLIC MODULATION MITOCHROMA RESEARCH, INC. (US) 2005-02-24 WO disclosed
WO-2005016268-A2 ALIMENTARY COMPOSITIONS AND METHODS FOR METABOLIC MODULATION MITOCHROMA RESEARCH, INC. (US) 2005-02-24 WO disclosed
EP-1414822-B1 IMPROVED SYNTHESIS OF BRANCHED ACYCLIC NUCLEOSIDES MEDIVIR AB (SE) 2005-02-16 EP disclosed
US-20040248910-A1 Synthesis of acyclic nucleoside derivatives MEDIVIR AB (SE) 2004-12-09 US disclosed
US-6808716-B2 N-acetylamino acids, related N-acetyl compounds and their topical use YU RUEY J (US) 2004-10-26 US disclosed
WO-2004089329-A2 TOPICAL COMPOSITIONS COMPRISING N-ACETYLAMINO ACIDS OR RELATED N-ACETYL COMPOUNDS YU RUEY J (US) 2004-10-21 WO disclosed
US-20040147743-A1 Synthesis of branched acyclic nucleosides BANK OF NEW YORK, THE 2004-07-29 US disclosed
EP-1414822-A1 IMPROVED SYNTHESIS OF BRANCHED ACYCLIC NUCLEOSIDES MEDIVIR AB (SE) 2004-05-06 EP disclosed
CN-1137892-C Preparation of N-9 substituted guanine compound - 2004-02-11 CN disclosed
US-20040024214-A1 Synthesis of acyclic nucleoside derivatives MEDIVIR AB (SE) 2004-02-05 US disclosed
US-20030229141-A1 N-acetyl cysteine and its topical use YU RUEY J (US) 2003-12-11 US disclosed
US-20030204079-A1 Process for producing 2', 3'-diethy substituted nucleoside derivatives AJINOMOTO CO., INC (JP) 2003-10-30 US disclosed
US-20030198656-A1 N-acetylamino acids, related N-acetyl compounds and their topical use YU RUEY J (US) 2003-10-23 US disclosed
US-6613936-B1 Herpes and retroviral infections; diester derivatives of H2G bearing specific combinations of an amino acid ester and a fatty acid ester, improved oral bioavailability; 9-(2-(butyryloxymethyl)-4-(L-isoleucyloxy)butyl)guanine MEDIVIR AB (SE) 2003-09-02 US disclosed
US-6579976-B2 Producing compounds having sugar-moiety hydroxyl groups or halogen atoms reduced in nucleic acids by allowing O-thiocarbonyl derivatives or halogenated derivatives in the sugar-moiety react with hypophosphorous acids or salts AJINOMOTO CO., INC. (JP) 2003-06-17 US disclosed
WO-2003002564-A1 IMPROVED SYNTHESIS OF BRANCHED ACYCLIC NUCLEOSIDES MEDIVIR AB (SE) 2003-01-09 WO disclosed
CN-1091445-C Internmediate of anti viral medicine, their preparation and use HUBEI PROV MEDICINE INDUSTRY I (CN) 2002-09-25 CN disclosed
EP-0882050-B1 PROCESS FOR PREPARING PURINE DERIVATIVES HOFFMANN LA ROCHE (CH) 2002-08-28 EP disclosed
US-20020045744-A1 PROCESS FOR PRODUCING NUCLEIC ACID DERIVATIVES AJINOMOTO CO., INC. (JP) 2002-04-18 US disclosed
US-6340756-B1 VIRICIDES SYNTEX (U.S.A.) INC. 2002-01-22 US disclosed
EP-0728757-B1 Process for producing purine derivatives AJINOMOTO KK (JP) 2001-10-04 EP disclosed
EP-1131323-A1 SYNTHESIS OF ACYCLIC NUCLEOSIDE DERIVATIVES Medivir Aktiebolag (SE) 2001-09-12 EP disclosed
CN-1301702-A Internmediate of anti viral medicine, their preparation and use HUBEI PROV MEDICINE INDUSTRY I (CN) 2001-07-04 CN disclosed
US-6245910-B1 Process for producing purine derivatives AJINOMOTO CO., INC. (JP) 2001-06-12 US disclosed
CN-1064683-C Process for preparing purine derivatives HOFFMANN LA ROCHE (CH) 2001-04-18 CN disclosed
US-6218568-B1 REACTING 1-ARALKYLOXY-3-HALO-2-PROPANOL WITH METHOXYMETHYL ALKANOATE IN APROTIC SOLVENT IN THE PRESENCE OF A CATALYST TO PRODUCE 1-ARALKYLOXY-3-HALO-2-(ALKANOYLOXY)METHOXYPROPANE AND TREATING THE PRODUCT WITH ALKALI METAL ALKANOATE SYNTEX (U.S.A.) INC. 2001-04-17 US disclosed
US-6215017-B1 1-ARALKYLOXY-3-ACYLOXY-2-(ACYLOXY)METHOXYPROPANE DERIVATIVE; CHEMICAL INTERMEDIATES FOR VIRICIDE GANCICLOVIR SYNTEX (U.S.A.) INC. 2001-04-10 US disclosed
US-6184376-B1 POTENT ANTIVIRALS, ESPECIALLY AGAINST HERPES INFECTIONS, SUCH AS THOSE CAUSED BY VARICELLA ZOSTER VIRUS, HERPES SIMPLEX, EPSTEIN-BARR VIRUS, HERPES TYPE 6 (HHV-6) AND TYPE 8 (HHV-8). SHINGLES IN THE ELDERLY OR CHICKEN POX IN THE YOUNG MEDIVER AB (SE) 2001-02-06 US disclosed
US-6087497-A DEBENZYLATION OF PURINE TO FORM VIRICIDES AJINOMOTO CO., INC. (JP) 2000-07-11 US disclosed
EP-0999218-A1 Process for producing nucleoside derivatives Ajinomoto Co., Inc. (JP) 2000-05-10 EP disclosed
CN-1051084-C Preparation of N-9 substituted guanine compounds HOFFMANN LA ROCHE (CH) 2000-04-05 CN disclosed
US-6040446-A Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative SYNTEX (U.S.A.) INC. (US) 2000-03-21 US disclosed
CN-1246477-A Preparation of N-9 substituted guanine compound HOFFMANN LA ROCHE (CH) 2000-03-08 CN disclosed
WO-2000008025-A1 SYNTHESIS OF ACYCLIC NUCLEOSIDE DERIVATIVES MEDIVIR AB (SE) 2000-02-17 WO disclosed
EP-0961775-A2 PURINE L-NUCLEOSIDES, ANALOGS AND USES THEREOF ICN Pharmaceuticals, Inc. (US) 1999-12-08 EP disclosed
US-5942617-A Process for producing purine derivatives AJINOMOTO CO., INC. (JP) 1999-08-24 US disclosed
EP-0704445-B1 Preparation of N-9 substituted guanine compounds HOFFMANN LA ROCHE (CH) 1999-04-21 EP disclosed
CN-1212693-A Process for preparing purine derivatives HOFFMANN LA ROCHE (CH) 1999-03-31 CN disclosed
EP-0882050-A1 PROCESS FOR PREPARING PURINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 1998-12-09 EP disclosed
US-5831092-A Process for producing purine derivatives AJINOMOTO CO., INC. (JP) 1998-11-03 US disclosed
US-5780607-A PYRANOSYL NUCLEOSIDE MONOMER UNITS CONNECTED BY AMIDE LINKAGES HOFFMANN-LA ROCHE INC. (US) 1998-07-14 US disclosed
WO-1998016184-A2 PURINE L-NUCLEOSIDES, ANALOGS AND USES THEREOF ICN PHARMACEUTICALS, INC. (US) 1998-04-23 WO disclosed
EP-0827960-A1 Process for producing purine derivatives Ajinomoto Co., Inc. (JP) 1998-03-11 EP disclosed
WO-1997027198-A1 PROCESS FOR PREPARING PURINE DERIVATIVES F.HOFFMANN-LA ROCHE AG (CH) 1997-07-31 WO disclosed
US-5648489-A PREPARING 9-((1,3-DIHYDROXY-2-PROPOXY)METHYL)GUANINE FROM A PROTECTED GUANINE AND 2-ACETOXYMETHOXY-1,3-DIACETOXYPROPANE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION (US) 1997-07-15 US disclosed
WO-1997014709-A1 ANTISENSE OLIGOMERS F. HOFFMANN-LA ROCHE AG (CH) 1997-04-24 WO disclosed
US-5583225-A REACTING N2, N9-DIPROTECTED GUANINE WITH DIACETOXYPROPANE IN THE PRESENCE OF A MIXTURE OF AN ACID AND ACETIC ANHYDRIDE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1996-12-10 US disclosed
US-5565565-A Preparation of N-9 substituted guanine compounds SYNTEX (U.S.A.) INC. (US) 1996-10-15 US disclosed
EP-0728757-A1 Process for producing purine derivatives Ajinomoto Co., Inc. (JP) 1996-08-28 EP disclosed
CN-1120044-A Preparation of N-9 substituted guanine compounds HOFFMANN LA ROCHE (US) 1996-04-10 CN disclosed
EP-0704445-A1 Preparation of N-9 substituted guanine compounds F. Hoffmann-La Roche AG (CH) 1996-04-03 EP disclosed
WO-1995011909-A1 PEPTIDE-BASED NUCLEIC ACID SURROGATES CASE WESTERN RESERVE UNIVERSITY (US) 1995-05-04 WO disclosed
US-5157120-A Guanine derivatives SYNTEX (U.S.A.) INC. (US) 1992-10-20 US disclosed
EP-0243670-B1 PURINE AND PYRIMIDINE COMPOUNDS AND THEIR USE AS ANTI-VIRAL AGENTS SYNTEX (U.S.A.) INC. (US) 1992-07-22 EP disclosed
EP-0049072-B1 GUANINE COMPOUNDS AND THEIR USE FOR THE PREPARATION OF ANTI-VIRAL AGENTS SYNTEX (U.S.A.) INC. (US) 1990-01-31 EP disclosed
US-4868187-A Anti-viral N-substituted pyrimidines SYNTEX (U.S.A.) INC. (US) 1989-09-19 US disclosed
EP-0243670-A1 Purine and pyrimidine compounds and their use as anti-viral agents SYNTEX (U.S.A.) INC. (US) 1987-11-04 EP disclosed
EP-0049072-A1 Guanine compounds and their use for the preparation of anti-viral agents SYNTEX (U.S.A.) INC. (US) 1982-04-07 EP disclosed
EP-0049072-A1 Guanine compounds and their use for the preparation of anti-viral agents SYNTEX (U.S.A.) INC. (US) 1982-04-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (26 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140369959-A1 4'-AZIDO, 3'-FLUORO SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF HCV RNA REPLICATION RNGTT, NSUN2, NSUN3 GDA 702/4885KDM4E 561/4885GAA 333/4885
US-20150152132-A1 Intermediate for Production of Nucleoside Analog and Method for Producing the Same RNGTT, NSUN2, RNMT GDA 119/4885KDM4E 2276/4885GAA 290/4885
US-20160068561-A9 Intermediate for Production of Nucleoside Analog and Method for Producing the Same RNGTT, NSUN2, RNMT GDA 119/4885KDM4E 2276/4885GAA 290/4885
US-20260117148-A1 SEMICONDUCTOR TREATMENT LIQUID, TREATMENT METHOD FOR OBJECT TO BE TREATED, AND MANUFACTURING METHOD OF ELECTRONIC DEVICE TPMT, P2RY13, TST GDA 1625/4885KDM4E 3987/4885GAA 1300/4885
US-12077548-B2 Substituted imidazoles for the inhibition of TGF-β and methods of treatment TGFB1, TGFBR1, TGFB2 GDA 4638/4885KDM4E 1077/4885GAA 1463/4885
US-11505815-B2 Compositions and methods related to non-templated enzymatic nucleic acid synthesis RNGTT, DUT, PNP GDA 83/4885KDM4E 1072/4885GAA 148/4885
US-20030204079-A1 Process for producing 2', 3'-diethy substituted nucleoside derivatives RNGTT, DOHH, NT5C3B GDA 228/4885KDM4E 2255/4885GAA 1356/4885
US-20120065386-A1 SYNTHESIS OF LABILE BASE PROTECTED - MODIFIED DEOXY & MODIFIED RIBO NUCLEOSIDES, CORRESPONDING PHOSPHORAMIDITES AND SUPPORTS AND THEIR USE IN HIGH PURITY OLIGONUCLEOTIDE SYNTHESIS RNMT, POLRMT, RNGTT GDA 69/4885KDM4E 4011/4885GAA 1180/4885
US-20070179290-A1 Production method of fluorinated purine nucleoside derivative, intermediate therefor and production method thereof PNP, NUDT1, ADAR GDA 104/4885KDM4E 3367/4885GAA 2820/4885
US-20090197332-A1 Modified Short Interfering RNA NSUN2, NSUN3, METTL16 GDA 1238/4885KDM4E 2497/4885GAA 2838/4885
US-12582656-B2 Nucleotide analogues RNGTT, PNP, RNMT GDA 457/4885KDM4E 2309/4885GAA 2381/4885
US-20050171126-A1 Process for the production of purine nucleoside compounds PNP, NUDT1, UMPS GDA 66/4885KDM4E 3453/4885GAA 932/4885
US-20230118992-A1 NUCLEOTIDE ANALOGUES PNP, NUDT1, RNGTT GDA 114/4885KDM4E 2971/4885GAA 1761/4885
US-20040024214-A1 Synthesis of acyclic nucleoside derivatives NSUN2, SLC28A1, NUDT1 GDA 578/4885KDM4E 4410/4885GAA 2583/4885
US-20220064187-A1 SUBSTITUTED IMIDAZOLES FOR THE INHIBITION OF TGF-BETA AND METHODS OF TREATMENT TGFB1, TGFBR1, TGFB2 GDA 4655/4885KDM4E 1114/4885GAA 1486/4885
US-20140221304-A1 5'-SUBSTITUTED NUCLEOSIDE ANALOGS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES NT5C3B, PNP, SLC29A1 GDA 102/4885KDM4E 2444/4885GAA 366/4885
US-20020045744-A1 PROCESS FOR PRODUCING NUCLEIC ACID DERIVATIVES RNGTT, OSGEP, PNP GDA 213/4885KDM4E 2751/4885GAA 1060/4885
US-20070161582-A1 Pharmaceutical compositions and methods for metabolic modulation GPR119, PRKAG2, PRKAG1 GDA 671/4885KDM4E 4093/4885GAA 907/4885
US-20040248910-A1 Synthesis of acyclic nucleoside derivatives NSUN2, SLC28A1, NUDT1 GDA 578/4885KDM4E 4410/4885GAA 2583/4885
US-20250017209-A1 COMPOSITION, MANUFACTURING METHOD FOR SEMICONDUCTOR ELEMENT, AND CLEANING METHOD FOR SEMICONDUCTOR SUBSTRATE SPOUT1, SRM, SMOX GDA 62/4885KDM4E 2023/4885GAA 164/4885
US-20190144905-A1 Novel Use DUT, RNGTT, MTAP GDA 158/4885KDM4E 1047/4885GAA 187/4885
US-20050250795-A1 Synthesis of acyclic nucleoside derivatives ASNS, NUDT1, PNP GDA 445/4885KDM4E 4268/4885GAA 2738/4885
US-20040147743-A1 Synthesis of branched acyclic nucleosides SI, POLL, ME1 GDA 153/4885KDM4E 1834/4885GAA 306/4885
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 GDA 488/4885KDM4E 3958/4885GAA 209/4885
US-20090203638-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR METABOLIC MODULATION GPR119, PRKAG2, GCKR GDA 656/4885KDM4E 4031/4885GAA 919/4885
US-20110237786-A1 METHOD FOR PREPARING OLIGONUCLEOTIDE POLRMT, POLR2H, RNGTT GDA 3894/4885KDM4E 4354/4885GAA 3384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.