Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 4/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28969071 | 1.00 | PPARA (0.55) | PPARAPPARGCASP1ITGB3ITGA2B | |
| SCHEMBL3569541 | 0.89 | MME (0.62) | PPARAPPARGCASP1ITGB3ITGA2B | |
| SCHEMBL1491365 | 0.89 | MME (0.62) | PPARAPPARGCASP1ITGB3ITGA2B | |
| SCHEMBL722757 | 0.89 | MME (0.62) | PPARAPPARGCASP1ITGB3ITGA2B | |
| SCHEMBL8760740 | 0.87 | PPARA (0.56) | PPARAPPARGCASP1ITGB3ITGA2B | |
| SCHEMBL613386 | 0.85 | CASP1 (0.67) | PPARAPPARGCASP1MMEECE1 | |
| SCHEMBL554032 | 0.85 | CASP1 (0.67) | PPARAPPARGCASP1MMEECE1 | |
| SCHEMBL376886 | 0.85 | CASP1 (0.67) | PPARAPPARGCASP1MMEECE1 | |
| SCHEMBL25022027 | 0.85 | SYK (0.54) | PPARAPPARGCASP1CTSK | |
| SCHEMBL2912589 | 0.84 | CASP1 (0.60) | PPARAPPARGCASP1CTSKTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115666553-A | TLR2 modulator compounds, and pharmaceutical compositions and uses thereof | 轴向治疗公司 | 2023-01-31 | — | — | CN | disclosed |