SCHEMBL1491365

SCHEMBL1491365

NC(=O)CC(NC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MME P08473 1/20 0.62
ECE1 P42892 1/20 0.62
PPARA Q07869 3/20 0.57
PPARG P37231 1/20 0.57
ALDH1A1 P00352 1/20 0.57
RAB9A P51151 1/20 0.57
PSMB1 P20618 1/20 0.55
CASP1 P29466 3/20 0.54
ITGB3 P05106 4/20 0.54
ITGA2B P08514 4/20 0.54
CTSK P43235 2/20 0.53
TACR1 P25103 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL722757 1.00 MME (0.62) MMEECE1PPARAPPARGALDH1A1
SCHEMBL3569541 1.00 MME (0.62) MMEECE1PPARAPPARGALDH1A1
SCHEMBL11124167 0.95 MME (0.64) MMEECE1PPARAPPARGALDH1A1
Phenylacetic Acid SCHEMBL1579412 0.93 CASP1 (0.58) MMEECE1PPARAPPARGALDH1A1
SCHEMBL8955765 0.91 CTSL (0.57) MMEECE1ALDH1A1PSMB1CASP1
SCHEMBL7688519 0.91 PSMB1 (0.57) MMEECE1PSMB1CASP1CTSK
SCHEMBL11121980 0.91 MME (0.60) MMEECE1PSMB1CASP1
SCHEMBL8078067 0.90 PSMB1 (0.56) MMEECE1PSMB1CASP1CTSK
SCHEMBL20495590 0.89 MME (0.61) MMEECE1PPARAPPARGPSMB1
SCHEMBL20495591 0.89 MME (0.61) MMEECE1PPARAPPARGPSMB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114682232-B Preparation method and application of bridged cyclodextrin/chitosan difunctional chiral monolithic column 福州大学 2023-04-21 CN claimed
CN-114682232-A Preparation method and application of bridged cyclodextrin/chitosan bifunctional chiral monolithic column 福州大学 2022-07-01 CN claimed
CN-112110834-A Modified hydrophobic auxiliary material and preparation method and application thereof 浙江智达药业有限公司 2020-12-22 CN claimed
US-5757408-A PRINTING IMAGE ON SUBSTRATE COATED WITH AMINO-ACID DERIVATIVE ADDITIVE; QUICK DRYING OF INK, OPTICAL DENSITY, NONCURLING XEROX CORPORATION (US) 1998-05-26 US claimed
US-5683793-A Ink jet transparencies XEROX CORPORATION (US) 1997-11-04 US claimed
US-5589277-A INK JET PRINTING, AQUEOUS INKS, FAST DRYING XEROX CORPORATION (US) 1996-12-31 US claimed
EP-0667246-A1 Recording sheets containing amino acids, hydroxy acids, and polycarboxyl compounds XEROX CORPORATION (US) 1995-08-16 EP claimed
US-12625431-B2 EUV resist underlayer film-forming composition NISSAN CHEMICAL CORPORATION (JP) 2026-05-12 US disclosed
EP-3985001-B1 PHARMACEUTICAL COMPOSITION FOR USE IN TREATING A CANCER SERVIER LAB (FR) 2026-04-29 EP disclosed
EP-4656638-A2 PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF Japan Tobacco Inc. (JP) 2025-12-03 EP disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
CN-118307534-A LTA4H inhibitors and uses thereof 上海海雁医药科技有限公司 2024-07-09 CN disclosed
EP-3377473-B1 MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS RQX PHARMACEUTICALS INC (US) 2024-06-19 EP disclosed
CN-1093701-A Antiretroviral hydrazine derivative CIBA GEIGY AG (CH) 1994-10-19 CN disclosed
CN-1068333-A Has hydrazine analog derivative of pharmacologically active and preparation method thereof CIBA GEIGY AG (CH) 1993-01-27 CN disclosed
EP-0490667-A2 HIV protease inhibitors JAPAN ENERGY CORPORATION (JP) 1992-06-17 EP disclosed
US-H642-H HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1989-06-06 US disclosed
US-4711952-A IMMUNOSTIMULATIVE, OR IMMUNOSUPPRESSORY AGENTS SPOFA, SPOJENE PODNIKY PRO ZDRAVOTNICKOUVYROBU (CS) 1987-12-08 US disclosed
EP-0232435-A2 Serum thymic factor peptide analogs and a process for the preparation thereof SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu (CS) 1987-08-19 EP disclosed
US-4237272-A BACTERICIDES KYOWA HAKKO KOGYO CO., LTD. (JP) 1980-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12625431-B2 EUV resist underlayer film-forming composition EEF1A1, ARF1, EMG1 MME 2475/4885ECE1 1982/4885PPARA 4500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.