SCHEMBL554032

SCHEMBL554032

O=C(O)CC(NC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 18/20 0.67
MME P08473 1/20 0.61
ECE1 P42892 1/20 0.61
PPARG P37231 1/20 0.56
PPARA Q07869 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL613386 1.00 CASP1 (0.67) CASP1MMEECE1PPARGPPARA
SCHEMBL376886 1.00 CASP1 (0.67) CASP1MMEECE1PPARGPPARA
SCHEMBL10605640 0.94 PPARA (0.62) CASP1MMEECE1PPARGPPARA
SCHEMBL10789378 0.94 MME (0.62) CASP1MMEECE1
SCHEMBL9069237 0.93 CASP1 (0.60) CASP1MMEECE1
SCHEMBL9069236 0.92 CASP1 (0.59) CASP1MMEECE1PPARGPPARA
SCHEMBL4280669 0.91 CASP1 (0.67) CASP1
SCHEMBL4280674 0.91 CASP1 (0.67) CASP1
SCHEMBL13589993 0.91 MME (0.65) MMEECE1
Tetrylammonium SCHEMBL14988987 0.91 CASP1 (0.58) CASP1MMEECE1PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112011495-B Recombinant escherichia coli for expressing thermolysin mutant and application thereof 江南大学 2022-12-16 CN claimed
CN-112011494-B Recombinant escherichia coli and application thereof in synthesis of aspartame through whole-cell transformation 江南大学 2022-12-02 CN claimed
CN-112011494-A Recombinant escherichia coli and application thereof in synthesis of aspartame through whole-cell transformation 江南大学 2020-12-01 CN claimed
CN-112011495-A Recombinant escherichia coli for expressing thermolysin mutant and application thereof 江南大学 2020-12-01 CN claimed
CN-109010830-A Application of the blood platelet related inhibitors in preparation treatment decrease of platelet disease drug 苏州大学 2018-12-18 CN claimed
CN-102234278-A (3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives, and synthesis method and application thereof UNIV CAPITAL MEDICAL 2011-11-09 CN claimed
CN-1889974-A Oligopeptides as coating material for medical products HEMOTEQ GMBH (DE) 2007-01-03 CN claimed
US-6395077-B1 INKS WITH BENZOYLBENZOIC ACID AND COLORS XEROX CORPORATION 2002-05-28 US claimed
EP-0640687-B1 Methods of using, storing and transporting metal protease enzyme in a stabilized form HOLLAND SWEETENER CO (NL) 2002-04-03 EP claimed
EP-0896056-A1 NOVEL THERMOLYSIN-LIKE PROTEASE AND USE THEREOF SAGAMI CHEMICAL RESEARCH CENTER (JP) 1999-02-10 EP claimed
WO-1995018133-A1 AMINO ALKANOIC ESTERS OF RAPAMYCIN AMERICAN HOME PRODUCTS CORPORATION (US) 1995-07-06 WO claimed
EP-0640687-A1 Methods of using, storing and transporting metal protease enzyme in a stabilized form HOLLAND SWEETENER COMPANY V.O.F. (NL) 1995-03-01 EP claimed
US-5336601-A Enzymatic membrane method for the snythesis and separation of peptides THE COCA-COLA COMPANY (US) 1994-08-09 US claimed
EP-0099585-B1 PROCESS FOR PRODUCING AN ADDITION COMPOUND OF A DIPEPTIDE ESTER AND AN AMINO ACID ESTER TOYO SODA MANUFACTURING CO., LTD. (JP) 1987-11-04 EP claimed
US-4521514-A Process for producing an addition compound of a dipeptide ester and an amino acid ester TOYO SODA MANUFACTURING CO., LTD. (JP) 1985-06-04 US claimed
EP-0072015-B1 METHOD FOR PURIFYING N-BENZYLOXYCARBONYL ASPARTIC ACID PPG INDUSTRIES, INC. (US) 1984-10-31 EP claimed
US-4450284-A Method for purifying N-benzyloxycarbonyl aspartic acid PPG INDUSTRIES, INC. (US) 1984-05-22 US claimed
EP-0099585-A1 Process for producing an addition compound of a dipeptide ester and an amino acid ester TOYO SODA MANUFACTURING CO., LTD. (JP) 1984-02-01 EP claimed
EP-0072015-A1 Method for purifying N-benzyloxycarbonyl aspartic acid PPG INDUSTRIES, INC. (US) 1983-02-16 EP claimed
US-4293706-A CARBAMYLATION, NEUTRALIZATION PPG INDUSTRIES, INC. (US) 1981-10-06 US claimed