Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25023302 | 1.00 | GRIA1 (0.47) | GRIA1PTPN1HDAC1HDAC6HDAC3 | |
| SCHEMBL25023290 | 0.91 | FAAH (0.46) | GRIA1PTPN1HDAC1HDAC6HDAC3 | |
| SCHEMBL30306849 | 0.84 | GRIA1 (0.47) | GRIA1PTPN1PLGPRSS1PRSS2 | |
| SCHEMBL28968987 | 0.84 | GRIA1 (0.47) | GRIA1PTPN1PLGPRSS1PRSS2 | |
| SCHEMBL28969062 | 0.84 | SIRT2 (0.51) | — | |
| SCHEMBL28969059 | 0.84 | SIRT2 (0.51) | — | |
| SCHEMBL28968977 | 0.84 | RARB (0.42) | HDAC1HDAC3RARBRARGFAAH | |
| SCHEMBL28968974 | 0.84 | RARB (0.42) | HDAC1HDAC3RARBRARGFAAH | |
| SCHEMBL25023280 | 0.81 | GRIA1 (0.47) | GRIA1PTPN1HDAC1HDAC6PLG | |
| SCHEMBL30306944 | 0.81 | GRIA1 (0.47) | GRIA1PTPN1HDAC1HDAC6PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115666553-A | TLR2 modulator compounds, and pharmaceutical compositions and uses thereof | 轴向治疗公司 | 2023-01-31 | — | — | CN | disclosed |