Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CHRND | Q07001 | 5/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.42 |
| ▸ | CHRNG | P07510 | 1/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30306849 | 1.00 | GRIA1 (0.47) | GRIA1PTPN1LPAR3LPAR1RARB | |
| SCHEMBL25022775 | 0.91 | LPAR3 (0.46) | GRIA1PTPN1LPAR3LPAR1CHRND | |
| SCHEMBL28969089 | 0.89 | RARB (0.44) | RARBRARGALDH1A1HPGDKDM4E | |
| SCHEMBL28969082 | 0.89 | RARB (0.44) | RARBRARGALDH1A1HPGDKDM4E | |
| SCHEMBL25023302 | 0.84 | GRIA1 (0.47) | GRIA1PTPN1LPAR3LPAR1RARB | |
| SCHEMBL28969085 | 0.84 | GRIA1 (0.47) | GRIA1PTPN1LPAR3LPAR1RARB | |
| SCHEMBL28969088 | 0.84 | HDAC8 (0.45) | RARBRARGALDH1A1HPGDKDM4E | |
| SCHEMBL28969078 | 0.84 | HDAC8 (0.45) | RARBRARGALDH1A1HPGDKDM4E | |
| SCHEMBL28968916 | 0.80 | GRIA1 (0.49) | GRIA1PTPN1LPAR3RARBRARG | |
| SCHEMBL28968965 | 0.80 | GRIA1 (0.47) | GRIA1PTPN1LPAR3LPAR1CHRND |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115666553-A | TLR2 modulator compounds, and pharmaceutical compositions and uses thereof | 轴向治疗公司 | 2023-01-31 | — | — | CN | disclosed |