Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 19/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 15/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 13/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28969059 | 1.00 | SIRT2 (0.51) | SIRT2SIRT1SIRT3MEN1ALDH1A1 | |
| SCHEMBL30306745 | 0.94 | SIRT2 (0.49) | SIRT2SIRT1SIRT3MEN1ALDH1A1 | |
| SCHEMBL30306910 | 0.92 | SIRT2 (0.51) | SIRT2SIRT1SIRT3MEN1ALDH1A1 | |
| SCHEMBL25023302 | 0.84 | GRIA1 (0.47) | — | |
| SCHEMBL28969085 | 0.84 | GRIA1 (0.47) | — | |
| SCHEMBL16601896 | 0.79 | CTSL (0.67) | SIRT2SIRT1SIRT3MEN1ALDH1A1 | |
| SCHEMBL28968977 | 0.79 | RARB (0.42) | — | |
| SCHEMBL28968974 | 0.79 | RARB (0.42) | — | |
| SCHEMBL6508639 | 0.79 | ATM (0.47) | ALDH1A1 | |
| SCHEMBL6254719 | 0.79 | NPPA (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115666553-A | TLR2 modulator compounds, and pharmaceutical compositions and uses thereof | 轴向治疗公司 | 2023-01-31 | — | — | CN | disclosed |