Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28969082 | 1.00 | RARB (0.44) | RARBRARGALDH1A1KDM4EHPGD | |
| SCHEMBL30306848 | 0.90 | MGLL (0.45) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL28968987 | 0.89 | GRIA1 (0.47) | RARBRARGALDH1A1KDM4EHPGD | |
| SCHEMBL30306849 | 0.89 | GRIA1 (0.47) | RARBRARGALDH1A1KDM4EHPGD | |
| SCHEMBL28969078 | 0.87 | HDAC8 (0.45) | RARBRARGALDH1A1KDM4EHPGD | |
| SCHEMBL28969088 | 0.87 | HDAC8 (0.45) | RARBRARGALDH1A1KDM4EHPGD | |
| SCHEMBL25022775 | 0.79 | LPAR3 (0.46) | FAAHCES1 | |
| SCHEMBL24073346 | 0.77 | MGLL (0.46) | HDAC8HDAC1HDAC2MAPT | |
| SCHEMBL7333177 | 0.77 | RARB (0.57) | RARBALDH1A1NPC1RAB9AHDAC8 | |
| SCHEMBL24073345 | 0.73 | MGLL (0.41) | ALDH1A1HDAC8FAAHCES1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115666553-A | TLR2 modulator compounds, and pharmaceutical compositions and uses thereof | 轴向治疗公司 | 2023-01-31 | — | — | CN | disclosed |