SCHEMBL28969856

SCHEMBL28969856

CCOC(=O)ONC(=O)C(N)CO

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
SOAT1 P35610 1/20 0.40
ALOX15 P16050 1/20 0.35
MGAM O43451 1/20 0.35
GAA P10253 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
SPHK1 Q9NYA1 2/20 0.34
KDM4E B2RXH2 1/20 0.33
PKM P14618 1/20 0.33
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
METAP2 P50579 3/20 0.32
METAP1 P53582 3/20 0.32
TLR2 O60603 1/20 0.32
CAD P27708 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28969889 0.84 ALDH1A1 (0.41) ALDH1A1SOAT1ALOX15MGAMGAA
SCHEMBL28969872 0.82 SLC7A5 (0.42) ALDH1A1SOAT1METAP2METAP1
SCHEMBL28969911 0.82 ALDH1A1 (0.40) ALDH1A1SOAT1ALOX15MGAMGAA
SCHEMBL28969882 0.81 ALDH1A1 (0.46) ALDH1A1SOAT1ALOX15MGAMGAA
SCHEMBL28969923 0.80 DPP4 (0.46) ALDH1A1SOAT1ALOX15MGAMGAA
SCHEMBL28969901 0.78 METAP2 (0.48) ALDH1A1SOAT1METAP2METAP1
SCHEMBL28969920 0.78 GNAI3 (0.50) TLR2
SCHEMBL28969885 0.78 ALDH1A1 (0.43) ALDH1A1SOAT1ALOX15MGAMGAA
SCHEMBL28969853 0.76 ALDH1A1 (0.41) ALDH1A1SOAT1SPHK1METAP2METAP1
SCHEMBL10651547 0.76 ALDH1A1 (0.36) ALDH1A1GAASPHK1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115835860-A Novel analogues of pterostilbene amino acids with carbonate for the treatment of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis 树顶分子生技股份有限公司 2023-03-21 CN disclosed