SCHEMBL28969867

SCHEMBL28969867

CC(OC(C)(C)C)C(NC(=O)OC(C)(C)C)C(=O)NCCO

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CTSK P43235 7/20 0.51
CTSS P25774 6/20 0.51
CA2 P00918 4/20 0.45
TDP1 Q9NUW8 1/20 0.42
CA1 P00915 1/20 0.41
CA7 P43166 1/20 0.41
CAPN1 P07384 1/20 0.41
CTSL P07711 2/20 0.40
CTSB P07858 2/20 0.40
CYP2D6 P10635 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28969869 0.87 CTSK (0.67) CTSKCTSSCA2TDP1CA1
SCHEMBL5559974 0.87 CTSK (0.67) CTSKCTSSCA2TDP1CA1
SCHEMBL28969873 0.83 CTSS (0.69) CTSKCTSSCA2TDP1CAPN1
SCHEMBL17880444 0.81 CTSK (0.47) CTSKCTSSCA2CA1CA7
SCHEMBL14737622 0.80 KMT2A (0.53) CTSKCTSSCA2TDP1CA1
SCHEMBL28969945 0.80 KMT2A (0.53) CTSKCTSSCA2TDP1CA1
SCHEMBL5741383 0.80 KMT2A (0.53) CTSKCTSSCA2TDP1CA1
SCHEMBL24097543 0.78 CTSK (0.63) CTSKCTSSCA2TDP1CA1
SCHEMBL29449290 0.78 CTSS (0.46) CTSKCTSSCA2CA1CA7
SCHEMBL6476152 0.77 CTSK (0.49) CTSKCTSSCA2CA1CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115835860-A Novel analogues of pterostilbene amino acids with carbonate for the treatment of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis 树顶分子生技股份有限公司 2023-03-21 CN disclosed