Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29083430 | 0.95 | TSHR (0.56) | APLNRTP53TSHRKMT2AMEN1 | |
| SCHEMBL29253168 | 0.91 | APLNR (0.50) | APLNRTP53TSHRKMT2AMEN1 | |
| SCHEMBL29253075 | 0.90 | APLNR (0.49) | APLNRTP53TSHRKMT2AMEN1 | |
| SCHEMBL29253093 | 0.88 | ALDH1A1 (0.50) | APLNRTP53TSHRKMT2AMEN1 | |
| SCHEMBL29253172 | 0.82 | STS (0.58) | KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL1530735 | 0.81 | APLNR (0.65) | APLNRTP53TSHRKMT2AMEN1 | |
| SCHEMBL28452492 | 0.80 | APLNR (0.63) | APLNRTP53TSHRKMT2AMEN1 | |
| SCHEMBL6050965 | 0.78 | HTT (0.58) | TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL28923208 | 0.77 | APLNR (0.59) | APLNRTP53TSHRKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL30620638 | 0.77 | HTT (0.56) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115836058-A | Benzisoxazole derivatives | 住友制药株式会社 | 2023-03-21 | — | — | CN | disclosed |