SCHEMBL28970802

SCHEMBL28970802

CSc1ccc(-c2ccoc2-c2ccco2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.38
ALDH1A1 P00352 6/20 0.37
KDM4E B2RXH2 5/20 0.37
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
BLM P54132 3/20 0.37
RAB9A P51151 3/20 0.37
NPC1 O15118 2/20 0.37
TAAR1 Q96RJ0 2/20 0.37
HPGD P15428 4/20 0.36
POLB P06746 4/20 0.36
HSD17B10 Q99714 3/20 0.36
USP2 O75604 2/20 0.36
TSHR P16473 1/20 0.36
MAPT P10636 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
ALOX15 P16050 2/20 0.36
PTPN7 P35236 2/20 0.36
RECQL P46063 2/20 0.36
TDP1 Q9NUW8 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18876468 0.81 TAAR1 (0.55) ALDH1A1KDM4EMEN1KMT2ABLM
SCHEMBL28445443 0.79 SMARCA2 (0.47) ALDH1A1KDM4EMEN1KMT2ABLM
SCHEMBL28970805 0.77 ADORA2A (0.48) ALDH1A1KDM4EMEN1KMT2ABLM
SCHEMBL10954891 0.75 MAPK14 (0.61) GSK3BALDH1A1PTGS2MAPK14PTGS1
SCHEMBL29695129 0.74 ALDH1A1 (0.44) GSK3BALDH1A1KDM4EMEN1KMT2A
SCHEMBL30375147 0.71 ALDH1A1 (0.41) ALDH1A1KDM4EMEN1KMT2ABLM
SCHEMBL29208511 0.71 MEN1 (0.56) ALDH1A1KDM4EMEN1KMT2AHPGD
SCHEMBL7255519 0.67 KDM4E (0.43) GSK3BALDH1A1KDM4ERAB9AHPGD
SCHEMBL7254182 0.66 PTGS2 (0.40) GSK3BALDH1A1KDM4ERAB9AHPGD
SCHEMBL23567064 0.65 ALDH1A1 (0.43) ALDH1A1KDM4EMEN1KMT2ABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115677627-B 2,2' -bisfuran compound, and preparation method and application thereof 华南理工大学 2024-04-12 CN disclosed
CN-115677627-A 2,2' -difuran compound and preparation method and application thereof 华南理工大学 2023-02-03 CN disclosed