Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7255519 | 0.81 | KDM4E (0.43) | PTGS2ALDH1A1KDM4EGLAGAA | |
| SCHEMBL7028615 | 0.74 | RAB9A (0.41) | PTGS2ALDH1A1KDM4EGLAGAA | |
| SCHEMBL7254570 | 0.70 | PTGS2 (0.43) | PTGS2ALDH1A1KDM4EGLAGAA | |
| SCHEMBL7257818 | 0.70 | PTGS1 (0.41) | PTGS2ALDH1A1KDM4EPTGS1 | |
| SCHEMBL7254196 | 0.70 | MAPK13 (0.39) | PTGS2ALDH1A1PTGS1AR | |
| SCHEMBL7024718 | 0.70 | KDM4E (0.35) | PTGS2ALDH1A1KDM4EGLAGAA | |
| SCHEMBL7254215 | 0.70 | KDM4E (0.50) | PTGS2ALDH1A1KDM4EGLAGAA | |
| SCHEMBL10954891 | 0.67 | MAPK14 (0.61) | PTGS2ALDH1A1PTGS1GSK3B | |
| SCHEMBL28970802 | 0.66 | GSK3B (0.38) | PTGS2ALDH1A1KDM4EGLAGAA | |
| SCHEMBL7030836 | 0.66 | GSK3B (0.47) | PTGS2ALDH1A1KDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006451-A1 | 4-PHENYLPYRAN-2-ONE DERIVATIVES | ALMIRALL PRODESFARMA S.A. (ES) | 2003-01-23 | — | — | WO | disclosed |