Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | POLA1 | P09884 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12972550 | 0.79 | TSHR (0.61) | LMNAALDH1A1TSHRRECQLEPHX2 | |
| SCHEMBL8076328 | 0.78 | TSHR (0.82) | LMNAALDH1A1TSHRRECQLEPHX2 | |
| SCHEMBL27953228 | 0.76 | TSHR (0.88) | LMNAALDH1A1TSHRRECQLEPHX2 | |
| SCHEMBL14975 | 0.76 | TSHR (0.88) | LMNAALDH1A1TSHRRECQLEPHX2 | |
| SCHEMBL8925728 | 0.75 | TSHR (0.68) | LMNAALDH1A1TSHRRECQLKMT2A | |
| SCHEMBL30336224 | 0.75 | FAAH (0.45) | ALDH1A1RECQLKMT2APOLBMEN1 | |
| Ethylene SCHEMBL11226694 | 0.74 | TSHR (0.74) | LMNAALDH1A1TSHRRECQLEPHX2 | |
| Ethylene SCHEMBL11220450 | 0.74 | TSHR (0.74) | LMNAALDH1A1TSHRRECQLEPHX2 | |
| SCHEMBL27782105 | 0.74 | FAAH (0.59) | LMNAALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL5367622 | 0.74 | ALDH1A1 (0.62) | LMNAALDH1A1TSHRRECQLEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113024423-B | Beta-fluoro, beta' -bissulfonylimide substituted ketone compound and preparation method and application thereof | 山东领海生物科技有限公司 | 2023-03-21 | — | — | CN | disclosed |